Evidence map›Paper›PMID 22905710›Full record

ReviewInternational wound journal2013

Wound treatment and pain management: a stressful time.

Kyoichi Matsuzaki, Dominic Upton

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in International wound journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07732036 (The Effectiveness and Acceptability of Inhalation Aromatherapy for Patients Undergoing Conservative Sharp Wound Debridement), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07732036 narecruitingnot on this mapstarted 2026, after this paper: background citation

The Effectiveness and Acceptability of Inhalation Aromatherapy for Patients Undergoing Conservative Sharp Wound Debridement: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorSingapore General HospitalRan2026 to 2028Enrolled40ConditionsAromatherapyArmsInhalation Aromatherapy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Validity of mental and physical stress models.Neuroscience and biobehavioral reviews · 2024
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Kyoichi MatsuzakiDepartment of Plastic and Reconstructive Surgery, Kawasaki Municipal Tama Hospital, Kawasaki.
Dominic UptonDepartment of Plastic and Reconstructive Surgery, Kawasaki Municipal Tama Hospital, Kawasaki, JapanDepartment of Plastic and Reconstructive Surgery, St. Marianna University School of Medicine, Kawasaki, JapanInstitute of Health and Society, University of Worcester, Worcester, UK.
Kawasaki Municipal Hospital · JPSt. Marianna University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review and case study report considers the evidence to indicate that the progress of wound healing is negatively affected by the presence of stressors and in circumstances where patients are in pain. It considers the relationship between perceptions of pain, stress and delayed wound healing with a specific focus on guidance for clinical practice. It is appreciated that although the literature has examined these issues in the management of acute wounds, demonstrating that psychological stress can have detrimental effects on the wound-healing process, the evidence to support this link in relation to chronic wounds is limited. The review considers evidence indicating that punch biopsy wounds heal more slowly in subjects under stress on account of caring for family members with long-term illnesses and also considers briefly the relationship between cortisol secretion in response to stress and the consequent influences on cytokine levels and the wound-healing process.

Indexed as

Disease ManagementWound HealingHumansPain ManagementStress, PsychologicalWounds and InjuriesChronic woundsCortisolCytokinesDelayed wound healingPainStress

Identifiers

PMID22905710
PMCPMC7950566
OpenAlexW2102897502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.