Evidence map›Paper›PMID 22905280›Full record

ArticleCurrent cardiovascular imaging reports2012

Imaging Cell Therapy for Myocardial Regeneration.

Hualei Zhang, Hui Qiao, Victor A Ferrari, Rong Zhou

Open access · greenAbstract read
In one paragraph

Article in Current cardiovascular imaging reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hualei ZhangLaboratories of Molecular Imaging, Department of Radiology, University of Pennsylvania, B6 Blockley Hall, 422 Curie Boulevard, Philadelphia, PA 19104, USA. Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA. Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Hui Qiao
Victor A Ferrari
Rong Zhou
Philadelphia University · USCardiovascular Institute of the South · US

Funding

Imaging Stem Cell Grafted in the Infarcted MyocardiumR01HL081185 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI ZHOU, RONG · 2006 to 2009
$1.9M
Assessment of Stem Cell Therapy of Infarcted MyocardiumR21EB002473 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ZHOU, RONG · 2003 to 2004
$436k
NHLBI NIH HHS R01 HL081185NIBIB NIH HHS R21 EB002473
6 · The paper itself

Abstract

Noninvasive or minimally invasive imaging techniques are essential for developing strategies and assessing outcomes of cell-based therapies for myocardial regeneration, also referred to as cellular cardiomyoplasty. Imaging-based monitoring of cell survival is useful for selection of optimal cell type and evaluating strategies to enhance engraftment. Imaging-derived surrogate end points including global and regional contractile function, myocardial blood flow, or perfusion and bioenergetics have been used in clinical trials or in relevant large animal models to evaluate the therapeutic effect and mechanisms of action of cellular cardiomyoplasty. New techniques are emerging to assess electrical integration of donor cells with host cardiomyocytes. This review will summarize and highlight important and informative findings revealed by imaging in clinical and preclinical cellular cardiomyoplasty studies over the past 3 years.

Identifiers

PMID22905280
PMCPMC3420065
OpenAlexW2017530856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.