Evidence map›Paper›PMID 22905036›Full record

ArticleAging health2012

Anxiety and verbal memory performance in APOE-4 carriers and noncarriers aged 50 years and above.

Ashley R Curiel, Karen J Miller, Karen Pollard, Jeanne Kim, Jena Kravitz, Gary W Small

Abstract read
In one paragraph

Article in Aging health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashley R CurielUniversity of California, Los Angeles, Semel Institute, 760 Westwood Plaza, Los Angeles, CA 90095, USA.
Karen J Miller
Karen Pollard
Jeanne Kim
Jena Kravitz
Gary W Small

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
ZDV &3TC NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFECTED INFANTS &M01RR000865 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WASHINGTON, ARNOLD E. · 1985 to 2011
$43.4M
UCLA ALZHEIMERS DISEASE RESEARCH CENTERP50AG016570 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BREDESEN, DALE E. · 1999 to 2014
$25.9M
VISUALIZING BRAIN A-BETA, TAU /SEROTONIN RECEPTOR DENSITP01AG025831 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SMALL, GARY WILLIAM · 2005 to 2010
$7.0M
FUNCTIONAL MRI FOR EARLY DIAGNOSIS OF ALZHEIMER'SR01AG013308 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOOKHEIMER, SUSAN Y · 1995 to 2011
$4.5M
Myelin integrity and Connectivity in Subjects at Risk for Alzheimer DiseaseF31AG035438 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BROWN, JESSE AARON · 2009 to 2012
$96k
UCLA ALZHEIMERS DISEASE CENTERP30AG010123 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CUMMINGS, JEFFREY L. · 1991 to 1998
–
FUNCTIONAL BRAIN IMAGING AND MENTAL DISORDERS IN AGINGR01MH052453 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SMALL, GARY WILLIAM · 1995 to 1999
–
NCATS NIH HHS UL1 TR000124NCRR NIH HHS M01 RR000865NIA NIH HHS F31 AG035438NIA NIH HHS P01 AG025831NIA NIH HHS P30 AG010123NIA NIH HHS P50 AG016570NIA NIH HHS R01 AG013308NIMH NIH HHS R01 MH052453
6 · The paper itself

Abstract

aimsThe current study sought to explore the relationship between state and trait anxiety and delayed verbal memory performance in APOE-4 carriers and noncarriers who were aged 50 years and above. MATERIALS #ENTITYSTARTX00026;

methodsThe study was a retrospective analysis of 267 participants aged 50 years and above who had completed genetic testing for APOE status, the State-Trait Anxiety Inventory, and a comprehensive neuropsychological battery that included three delayed verbal memory measures (Wechsler Memory Scale - 3rd Edition, Logical Memory and Verbal Pairs subtests and the Buschke Selective Reminding Test).

resultsAn inverse relationship was found between state anxiety and delayed verbal memory performance. No difference in level of anxiety was found between APOE-4 carriers versus noncarriers.

conclusionState anxiety, but not trait anxiety, was found to have an inverse relationship with delayed verbal memory performance. For example, as self-reported state anxiety increased, delayed verbal memory scores decreased. This relationship did not appear to be influenced by the presence or absence of the APOE-4 allele.

Identifiers

PMID22905036
PMCPMC3420064

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.