Evidence map›Paper›PMID 22904687›Full record

ArticlePLoS biology2012

The Human Microbiome Project: a community resource for the healthy human microbiome.

Dirk Gevers, Rob Knight, Joseph F Petrosino, Katherine Huang, Amy L McGuire, Bruce W Birren, Karen E Nelson, Owen White, Barbara A Methé, Curtis Huttenhower

Registry-linked trialAbstract read
In one paragraph

Article in PLoS biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04784260 (Microbiome Influence on Seminal Quality on Semen Donors), which is not on this map. Cited by 243 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
243citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04784260 completednot on this mapstarted 2020, after this paper: background citation

Microbiome Influence on Seminal Quality on Semen Donors

TypeobservationalSponsorInstituto Valenciano de Infertilidad, IVI AlicanteRan2020 to 2023Enrolled40ConditionsInfertility, MaleArmsMicrobiome analysis
3 · Its place in the literature

Who cites it

243 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  6. The Human Microbiome in Relation to Cancer Risk: A Systematic Review of Epidemiologic Studies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Pooled it
  7. Pooled it
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  9. Trial
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  12. Review
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183 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dirk GeversThe Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.
Rob Knight
Joseph F Petrosino
Katherine Huang
Amy L McGuire
Bruce W Birren
Karen E Nelson
Owen White
Barbara A Methé
Curtis Huttenhower

Funding

Large Scale Sequencing and Analysis of GenomesU54HG003067 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GABRIEL, STACEY, LANDER, ERIC S · 2004 to 2015
$568.6M
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
A Quality Assurance, Coordination and Analysis Center for HMPU01HG004866 · NHGRI · UNIVERSITY OF MARYLAND BALTIMORE · PI WHITE, OWEN R · 2008 to 2012
$12.5M
Construction Of A Reference Sequence Data Set For The Human Microbiome ProjectU54AI084844 · NIAID · J. CRAIG VENTER INSTITUTE, INC. · PI NELSON, KAREN E. · 2009 to 2012
$10.3M
Defining the Human MicrobiomeU54HG004969 · NHGRI · BROAD INSTITUTE, INC. · PI BIRREN, BRUCE W. · 2009 to 2012
$10.3M
New Tools for Understanding the Composition and Dynamics of Microbial CommunitiesR01HG004872 · NHGRI · UNIVERSITY OF COLORADO · PI KNIGHT, ROB · 2008 to 2012
$1.8M
A Microbial Genome Reference Platform for MetagenomicsU54HG004973 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A, HIGHLANDER, SARAH KATHERINE · 2009 to 2010
$1.8M
Functional activity and inter-organismal interactions in the human microbiomeR01HG005969 · NHGRI · HARVARD SCHOOL OF PUBLIC HEALTH · PI HUTTENHOWER, CURTIS · 2010 to 2012
$1.3M
Howard Hughes Medical InstituteNHGRI NIH HHS R01 HG004872NHGRI NIH HHS R01HG004872NHGRI NIH HHS R01 HG005969NHGRI NIH HHS R01HG005969NHGRI NIH HHS U01 HG004866NHGRI NIH HHS U01HG004866NHGRI NIH HHS U54 HG003067NHGRI NIH HHS U54 HG004969NHGRI NIH HHS U54HG004969NHGRI NIH HHS U54 HG004973NHGRI NIH HHS U54HG004973NIAID NIH HHS U54 AI084844NIAID NIH HHS U54AI084844NIDDK NIH HHS P30 DK043351
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GenomicsInternetMetagenomeComputational BiologyEcosystemGenes, rRNAHealthHigh-Throughput Nucleotide SequencingHumansOrganizationsPhylogenyRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID22904687
PMCPMC3419203

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.