ArticleJournal of histotechnology2012
Genetically modified species in research: Opportunities and challenges for the histology core laboratory.
Article in Journal of histotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Immune contexture analysis in immuno-oncology: applications and challenges of multiplex fluorescent immunohistochemistry.Clinical & translational immunology · 2020Review
- Histopathologic Evaluation and Scoring of Viral Lung Infection.Methods in molecular biology (Clifton, N.J.) · 2020Review
- [Histopathological research laboratories in translational research : Conception and integration into the infrastructure of pathological institutes].Der Pathologe · 2019Article
- Allograft Inflammatory Factor 1 as an Immunohistochemical Marker for Macrophages in Multiple Tissues and Laboratory Animal Species.Comparative medicine · 2018Article
- Principles and approaches for reproducible scoring of tissue stains in research.Laboratory investigation; a journal of technical methods and pathology · 2018Review
- Approaches to Evaluate Lung Inflammation in Translational Research.Veterinary pathology · 2018Review
- Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2017Article
- Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans.Toxicologic pathology · 2016Article
- Immunohistochemical detection of arginase-I expression in formalin-fixed lung and other tissues.Journal of histotechnology · 2013Article
- Principles for valid histopathologic scoring in research.Veterinary pathology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Translational research using animal models has traditionally involved genetically modified rodents; however there is increasing use of other novel genetically engineered species. As histology laboratories interface with researchers studying these novel species there will be many situations in which protocols will need to be adapted to the species, model and research goals. This paper gives examples of protocol adaptations to meet research needs and addresses common considerations that should be addressed for all research tissues submitted to the histotechnology laboratory. Positioning the histotechnologist, as well as the investigator, to meet the challenges associated with novel research models will help maximize research efficacy and quality.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.