Why genomics shouldn't get too personal: in favor of filters: Re: invited comment by Holly K. Tabor et al. in American Journal of Medical Genetics Part A Volume 155.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

7 citing papers in PubMed.

1. Ethical values supporting the disclosure of incidental and secondary findings in clinical genomic testing: a qualitative study.BMC medical ethics · 2020
   Article
2. Ethical Considerations for the Return of Incidental Findings in Ophthalmic Genomic Research.Translational vision science & technology · 2016
   Article
3. Ethical signposts for clinical geneticists in secondary variant and incidental finding disclosure discussions.Medicine, health care, and philosophy · 2015
   Article
4. So rare we need to hunt for them: reframing the ethical debate on incidental findings.Genome medicine · 2015
   Article
5. PhenoVar: a phenotype-driven approach in clinical genomics for the diagnosis of polymalformative syndromes.BMC medical genomics · 2014
   Article
6. Secondary variants--in defense of a more fitting term in the incidental findings debate.European journal of human genetics : EJHG · 2013
   Article
7. Practices and policies of clinical exome sequencing providers: analysis and implications.American journal of medical genetics. Part A · 2013
   Article

Corrections and comments

• Comment on
  Genomics really gets personal: how exome and whole genome sequencing challenge the ethical framework of human genetics research.2011

Authors and funding

4 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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