Evidence map›Paper›PMID 22903393›Full record

ArticleArchives of virology2012

Genetic characterization of an isolate of HIV type 1 AG recombinant form circulating in Siberia, Russia.

P B Baryshev, V V Bogachev, N M Gashnikova

Registry-linked trialAbstract read
In one paragraph

Article in Archives of virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05322083 (Analysis of HIV Subtype A6 Genome in Patients With Virological Failure After Switching to Doravirine), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05322083 unknown statusnot on this mapstarted 2022, after this paper: background citation

Analysis of HIV Subtype A6 Genome in Patients With Virological Failure After Switching to Doravirine (DOR)

TypeobservationalSponsorGamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian FederationRan2022 to 2024Enrolled60ConditionsVirus-HIVArmsDoravirine
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Characterization of HIV-1 Epidemic in Kyrgyzstan.Frontiers in microbiology · 2021
    Article
  6. Article
  7. Article
  8. Overview of HIV molecular epidemiology among people who inject drugs in Europe and Asia.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2016
    Review
  9. Article
  10. Article
  11. Article
  12. HIV-1 genetic variants in the Russian Far East.AIDS research and human retroviruses · 2014
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

P B BaryshevState Research Center of Virology and Biotechnology VECTOR, Novosibirsk, Russia. baryshev_pb@vector.nsc.ru
V V Bogachev
N M Gashnikova

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Before 2008, HIV-1 subtype A was the predominant genetic variant in the Novosibirsk oblast of Russia as well as in most parts of this country. However, a rapid spread of the recombinant HIV-1 02_AG form has been reported in Novosibirsk since 2009. We have analyzed the genome of the 10.RU.6637 isolate, a HIV-1 02_AG recombinant form, which represents a monophyletic cluster of the HIV-1 variants widespread in this region. Phylogenetic analysis has shown that the Siberian 10.RU.6637 isolate displays the highest sequence identity to the HIV-1 subtype AG forms circulating in Uzbekistan. However, recombination analysis of 10.RU.6637 has demonstrated that this isolate is a recombinant form between HIV-1 subtype A and CRF02_AG, differing in its genetic structure from both the CRF02_AG reference sequences and the Central Asian variants of HIV-1 02_AG.

Indexed as

Genetic VariationAdultBase SequenceEpidemicsGenome, ViralGenotypeHIV-1HIV InfectionsHumansMaleMolecular Sequence DataPhylogenyReassortant VirusesRisk FactorsSiberiaUzbekistan

Identifiers

PMID22903393
PMCPMC3506197

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.