Evidence map›Paper›PMID 22903262›Full record

ReviewCellular and molecular life sciences : CMLS2012

The molecular mechanism of zinc and cadmium stress response in plants.

Ya-Fen Lin, Mark G M Aarts

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 168 papers.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed
35.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 649 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
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  6. Article
  7. Article
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  9. Article
  10. 24-Epibrassinolide modulates antioxidant regulation and redox homeostasis in soybean exposed to cadmium stress.Physiology and molecular biology of plants : an international journal of functional plant biology · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Screening of In Vitro Heavy Metal Tolerance inPlants (Basel, Switzerland) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Physiological and proteomic analysis of halophyteFrontiers in plant science · 2025
    Article
  20. Article

108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ya-Fen LinLaboratory of Genetics, Wageningen University, The Netherlands. ya-fen.lin@wur.nl
Mark G M Aarts
Wageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When plants are subjected to high metal exposure, different plant species take different strategies in response to metal-induced stress. Largely, plants can be distinguished in four groups: metal-sensitive species, metal-resistant excluder species, metal-tolerant non-hyperaccumulator species, and metal-hypertolerant hyperaccumulator species, each having different molecular mechanisms to accomplish their resistance/tolerance to metal stress or reduce the negative consequences of metal toxicity. Plant responses to heavy metals are molecularly regulated in a process called metal homeostasis, which also includes regulation of the metal-induced reactive oxygen species (ROS) signaling pathway. ROS generation and signaling plays an important duel role in heavy metal detoxification and tolerance. In this review, we will compare the different molecular mechanisms of nutritional (Zn) and non-nutritional (Cd) metal homeostasis between metal-sensitive and metal-adapted species. We will also include the role of metal-induced ROS signal transduction in this comparison, with the aim to provide a comprehensive overview on how plants cope with Zn/Cd stress at the molecular level.

Indexed as

Stress, PhysiologicalBiological AvailabilityCadmiumPlant Physiological PhenomenaPlantsReactive Oxygen SpeciesSignal TransductionZincCadmiumReactive Oxygen SpeciesZinc

Identifiers

PMID22903262
PMCPMC11114967
OpenAlexW2026178384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.