Evidence map›Paper›PMID 22903019›Full record

ReviewThe international journal of biochemistry & cell biology2012

The role of recipient T cells in mesenchymal stem cell-based tissue regeneration.

Yi Liu, Songlin Wang, Songtao Shi

Open access · greenAbstract readReview
In one paragraph

Review in The international journal of biochemistry & cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

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  11. CD8Frontiers in immunology · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Yi LiuFaculty of Periodontics, Capital Medical University School of Stomatology, Tian Tan Xi Li No 4, Beijing 100050, China.
Songlin Wang
Songtao Shi
Capital Medical University · CNUniversity of Southern California · US

Funding

OSTEOGENIC MECHANISMS OF SHEDR01DE017449 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHI, SONGTAO · 2007 to 2017
$3.5M
GINGIVA DERIVED MSCS: ROLE IN IMMUNOMODULATION AND TISSUE REGENERATIONR01DE019932 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LE, ANH D, SHI, SONGTAO · 2009 to 2013
$2.8M
NIDCR NIH HHS R01 DE017449NIDCR NIH HHS R01DE017449NIDCR NIH HHS R01 DE019932NIDCR NIH HHS R01DE019932
6 · The paper itself

Abstract

Significant progress has been made in stem cell biology, regenerative medicine, and stem cell-based tissue engineering. Such scientific strides highlight the potential of replacing or repairing damaged tissues in congenital abnormalities, diseases, or injuries, as well as constructing functional tissue or organs in vivo. Since mesenchymal stem cells (MSCs) are capable of differentiating into bone-forming cells, they constitute an appropriate cell source to repair damaged bone tissues. In addition, the immunoregulatory property of MSCs provides a foundation for their use in treating a variety of autoimmune diseases. However, the interaction between MSCs and immune cells in cell-based tissue regeneration is largely unknown. In this review, we will discuss the current understanding of MSC-based tissue regeneration, emphasizing the role of the immune microenvironment in bone regeneration.

Indexed as

Bone RegenerationCellular MicroenvironmentHumansImmunomodulationInflammationMesenchymal Stem CellsT-Lymphocytes

Identifiers

PMID22903019
PMCPMC3454862
OpenAlexW2034010324

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.