ArticlePlant signaling & behavior2012
Nitric oxide and glutathione impact the expression of iron uptake- and iron transport-related genes as well as the content of metals in A. thaliana plants grown under iron deficiency.
Article in Plant signaling & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Enhancing plant drought tolerance through exogenous nitric oxide: a comprehensive meta-analysis.BMC plant biology · 2025Pooled it
- Signaling function of NHPlanta · 2024Article
- NO Is Not the Same as GSNO in the Regulation of Fe Deficiency Responses by Dicot Plants.International journal of molecular sciences · 2023Review
- Editorial: Role of shoot-derived signals in root responses to environmental changes.Frontiers in plant science · 2023Article
- A shoot derived long distance iron signal may act upstream of the IMA peptides in the regulation of Fe deficiency responses inFrontiers in plant science · 2022Article
- Ethylene and Nitric Oxide Involvement in the Regulation of Fe and P Deficiency Responses in Dicotyledonous Plants.International journal of molecular sciences · 2021Review
- Induced Systemic Resistance (ISR) and Fe Deficiency Responses in Dicot Plants.Frontiers in plant science · 2019Review
- A Shoot Fe Signaling Pathway Requiring the OPT3 Transporter Controls GSNO Reductase and Ethylene inFrontiers in plant science · 2018Article
- Nitric oxide ameliorates the damaging effects of oxidative stress induced by iron deficiency in cyanobacterium Anabaena 7120.Environmental science and pollution research international · 2016Article
- Interactive effects of nitric oxide and glutathione in mitigating copper toxicity of rice (Oryza sativa L.) seedlings.Plant signaling & behavior · 2015Article
- Nitric Oxide Alleviated Arsenic Toxicity by Modulation of Antioxidants and Thiol Metabolism in Rice (Oryza sativa L.).Frontiers in plant science · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mounting evidence indicate that nitric oxide (NO) acts as a signaling molecule mediating iron deficiency responses through the upregulation of the expression of iron uptake-related genes. Accordingly, NO donors such as nitrosoglutathione (GSNO) were reported to improve the fitness of plants grown under iron deficiency. Here, we showed that glutathione, a by-product of GSNO, triggered the upregulation of the expression of iron uptake- and transport-related gene and an increase of iron concentration in Arabidopsis thaliana seedlings facing iron deficiency. Furthermore, we provided evidence that under iron deficiency, NO released by GSNO did not improve the root iron concentration but impacted the content of copper. Collectively, our data highlight the complexity of interpreting data based on the use of NO donors when investigating the role of NO in iron homeostasis.
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Registered trials
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