ReviewNutrition, metabolism, and cardiovascular diseases : NMCD2013
Endothelial function and the regulation of muscle protein anabolism in older adults.
Review in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 50 citations in OpenAlex.
- Trial
- Impact of low-intensity resistance and whole-body vibration training on aortic hemodynamics and vascular function in postmenopausal women.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Trial
- Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults.Experimental gerontology · 2019Trial
- Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial.The British journal of nutrition · 2015Trial
- Vascular aging as a driver of organ dysfunction and systemic aging.Nature cardiovascular research · 2026Review
- Bile Acid Metabolism Affects Muscle Regeneration in Aging Skeletal Muscle in a Manner Associated with Regulation of ABCB1 Expression.International journal of molecular sciences · 2026Article
- Association of kidney function with physical performance: the Maastricht study.Journal of nephrology · 2024Article
- Sarcopenia is independently associated with poor preoperative physical fitness in patients undergoing colorectal cancer surgery.Journal of cachexia, sarcopenia and muscle · 2024Article
- Sarcopenic obesity in older adults: a clinical overview.Nature reviews. Endocrinology · 2024Review
- The Relationship Between Sarcopenia And Proteinuria, What Do We Know?Current aging science · 2024Review
- Association of Vascular Health Measures and Physical Function: A Prospective Analysis in the Framingham Heart Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Sarcopenia and Cardiovascular Diseases.Circulation · 2023Review
- Sarcopenia and cardiovascular disease in patients with and without kidney disease: what do we know?International urology and nephrology · 2023Review
- Major dietary patterns in relation to muscle strength status among middle-aged people: A cross-sectional study within the RaNCD cohort.Food science & nutrition · 2021Article
- Single-Cell Transcriptional Profiling Reveals Sex and Age Diversity of Gene Expression in Mouse Endothelial Cells.Frontiers in genetics · 2021Article
- Article
- Physical activity and exercise: Strategies to manage frailty.Redox biology · 2020Review
- Increased arterial velocity pulse index is an independent factor related to skeletal muscle mass reduction and tissue damage in patients with cardiovascular disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- [Correlation between sarcopenia and albuminuria in patients with type 2 diabetes].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Metabolic and Nutritional Characteristics in Middle-Aged and Elderly Sarcopenia Patients with Type 2 Diabetes.Journal of diabetes research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Sarcopenia, the loss of skeletal muscle mass and function with aging, is a major contributor to frailty and morbidity in older adults. Recent evidence has emerged suggesting that endothelial dysfunction and insulin resistance of muscle protein metabolism may significantly contribute to the development of sarcopenia. In this article we review: 1) recent studies and theories on the regulation of skeletal muscle protein balance in older adults; 2) the link between insulin resistance of muscle protein synthesis and endothelial dysfunction in aging; 3) mechanisms for impaired endothelial responsiveness in aging; and 4) potential treatments that may restore the endothelial responsiveness and muscle protein anabolic sensitivity in older adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.