Evidence map›Paper›PMID 22902004›Full record

ArticleMetabolism: clinical and experimental2012

Exercise training improves hemodynamic recovery to isometric exercise in obese men with type 2 diabetes but not in obese women.

Jill A Kanaley, Styliani Goulopoulou, Ruth Franklin, Tracy Baynard, Robert L Carhart, Ruth S Weinstock, Bo Fernhall

Abstract read
In one paragraph

Article in Metabolism: clinical and experimental, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Jill A KanaleyDepartment of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO, USA. kanaleyj@missouri.edu
Styliani Goulopoulou
Ruth Franklin
Tracy Baynard
Robert L Carhart
Ruth S Weinstock
Bo Fernhall
SUNY Upstate Medical University · USUniversity of Illinois Chicago · USSyracuse University · USUniversity of Illinois Urbana-Champaign · USUniversity of Missouri · US

Funding

Autonomic Function and Exercise in Type 2 DiabeticsR21DK063179 · NIDDK · SYRACUSE UNIVERSITY · PI KANALEY, JILL A · 2004 to 2005
$290k
NIDDK NIH HHS R21 DK063179NIDDK NIH HHS R21DK063179
6 · The paper itself

Abstract

objectivesWomen with type 2 diabetes (T2D) show greater rates of mortality due to ischemic heart disease than men with T2D. We aimed to examine cardiovascular and autonomic function responses to isometric handgrip (IHG) exercise between men and women with T2D, before and after an exercise training program. MATERIALS/

methodsHemodynamic responses were measured in 22 men and women with T2D during and following a 3-min IHG test, and before and after 16 wks of aerobic exercise training.

resultsWomen had a smaller decrease in mean arterial pressure (MAP) and systolic blood pressure (BP) during recovery from IHG (ΔMAP(REC)) than men pre- and post-training (P<0.05). Men showed a greater reduction in diastolic BP during recovery from IHG (P<0.05), and exercise training improved this response in men but not in women (men, pre-training: -13.9±1.8, post-training: -20.5±5.3 mmHg vs. women, pre-training: -10.7±1.7, post-training: -4.1±4.9 mmHg; P<0.05). Men had a greater reduction in sympathetic modulation of vasomotor tone (P<0.05), as estimated by blood pressure variability, following IHG. This response was accentuated after training, while this training effect was not seen in women. Post-training ΔMAP(REC) was correlated with recovery of low frequency component of the BP spectrum (ΔLF(SBPrec), r=0.52, P<0.05).

conclusionsDifferences in BP recovery immediately following IHG may be attributed to gender differences in cardiovascular autonomic modulation. An improvement in these responses occurs following aerobic exercise training in obese men, but not in obese women with T2D which reflects a better adaptive autonomic response to exercise training.

Indexed as

Blood PressureExerciseHand StrengthHeart RateIsometric ContractionAdultAgedAntihypertensive AgentsArterial PressureBaroreflexDiabetes Mellitus, Type 2Glucose Tolerance TestGlycated HemoglobinHumansHypoglycemic AgentsHypolipidemic AgentsAntihypertensive AgentsGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsHypolipidemic Agents

Identifiers

PMID22902004
PMCPMC3504623
OpenAlexW2031970892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.