ArticleInternational journal of evolutionary biology2012
Polyploidy and the evolution of complex traits.
Article in International journal of evolutionary biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Ancient allopolyploidy and specific subgenomic evolution drove the radiation of poplars and willows.Nature communications · 2025Article
- Higher order polyploids exhibit enhanced desiccation tolerance in the grass Microchloa caffra.Journal of experimental botany · 2024Article
- Cancer evolution: Darwin and beyond.The EMBO journal · 2021Review
- Temporal patterns of diversification in Brassicaceae demonstrate decoupling of rate shifts and mesopolyploidization events.Annals of botany · 2020Article
- Homeobox Gene Duplication and Divergence in Arachnids.Molecular biology and evolution · 2018Article
- Expression properties exhibit correlated patterns with the fate of duplicated genes, their divergence, and transcriptional plasticity in Saccharomycotina.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Pervasive microRNA Duplication in Chelicerates: Insights from the Embryonic microRNA Repertoire of the Spider Parasteatoda tepidariorum.Genome biology and evolution · 2016Article
- Evolution history of duplicatedPeerJ · 2016Article
- MicroRNA profiles reveal female allotetraploid hybrid fertility.BMC genetics · 2015Article
- A synergism between adaptive effects and evolvability drives whole genome duplication to fixation.PLoS computational biology · 2014Article
- Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.Cancer discovery · 2014Article
- Whole-genome duplication and hemoglobin differentiation traits between allopatric populations of Brazilian Odontophrynus americanus species complex (Amphibia, Anura).Genetics and molecular biologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We explore how whole-genome duplications (WGDs) may have given rise to complex innovations in cellular networks, innovations that could not have evolved through sequential single-gene duplications. We focus on two classical WGD events, one in bakers' yeast and the other at the base of vertebrates (i.e., two rounds of whole-genome duplication: 2R-WGD). Two complex adaptations are discussed in detail: aerobic ethanol fermentation in yeast and the rewiring of the vertebrate developmental regulatory network through the 2R-WGD. These two examples, derived from diverged branches on the eukaryotic tree, boldly underline the evolutionary potential of WGD in facilitating major evolutionary transitions. We close by arguing that the evolutionary importance of WGD may require updating certain aspects of modern evolutionary theory, perhaps helping to synthesize a new evolutionary systems biology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.