ReviewNeural plasticity2012
Activity-dependent plasticity of spinal circuits in the developing and mature spinal cord.
Review in Neural plasticity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Ia excitatory postsynaptic potentials are potentiated in slow-type motoneurons after a 5-week treadmill endurance training in rats.European journal of applied physiology · 2026Article
- Functional symmetrization of neuromotor modules during locomotor development in human infants.Communications biology · 2025Article
- Review
- Quadriceps Weakness is Associated with Neuroplastic Changes Within Specific Corticospinal Pathways and Brain Areas After Anterior Cruciate Ligament Reconstruction: Theoretical Utility of Motor Imagery-Based Brain-Computer Interface Technology for Rehabilitation.Arthroscopy, sports medicine, and rehabilitation · 2023Article
- Relationship of strength, joint kinesthesia, and plantar tactile sensation to dynamic and static postural stability among patients with anterior cruciate ligament reconstruction.Frontiers in physiology · 2023Article
- Modulations of corticospinal excitability following rapid ankle dorsiflexion in skill- and endurance-trained athletes.European journal of applied physiology · 2022Article
- A model for self-organization of sensorimotor function: spinal interneuronal integration.Journal of neurophysiology · 2022Article
- When Spinal Neuromodulation Meets Sensorimotor Rehabilitation: Lessons Learned From Animal Models to Regain Manual Dexterity After a Spinal Cord Injury.Frontiers in rehabilitation sciences · 2021Review
- Early Neonatal Pain-A Review of Clinical and Experimental Implications on Painful Conditions Later in Life.Frontiers in pediatrics · 2020Review
- The Role of Carotid Sinus Nerve Input in the Hypoxic-Hypercapnic Ventilatory Response in Juvenile Rats.Frontiers in physiology · 2020Article
- Dry immersion as a model of deafferentation: A neurophysiology study using somatosensory evoked potentials.PloS one · 2018Article
- Article
- Development and aging of human spinal cord circuitries.Journal of neurophysiology · 2017Review
- Passive cycling in neurorehabilitation after spinal cord injury: A review.The journal of spinal cord medicine · 2017Review
- Article
- Functional Recovery from Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training in Mice with Chronic Spinal Cord Injury.Scientific reports · 2016Article
- Spinal circuits can accommodate interaction torques during multijoint limb movements.Frontiers in computational neuroscience · 2014Article
- Dual effects of brain sparing opioid in newborn rats: Analgesia and hyperalgesia.Neurobiology of pain (Cambridge, Mass.)Article
- Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology.Critical reviews in biochemistry and molecular biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Part of the development and maturation of the central nervous system (CNS) occurs through interactions with the environment. Through physical activities and interactions with the world, an animal receives considerable sensory information from various sources. These sources can be internally (proprioceptive) or externally (such as touch and pressure) generated senses. Ample evidence exists to demonstrate that the sensory information originating from large diameter afferents (Ia fibers) have an important role in inducing essential functional and morphological changes for the maturation of both the brain and the spinal cord. The Ia fibers transmit sensory information generated by muscle activity and movement. Such use or activity-dependent plastic changes occur throughout life and are one reason for the ability to acquire new skills and learn new movements. However, the extent and particularly the mechanisms of activity-dependent changes are markedly different between a developing nervous system and a mature nervous system. Understanding these mechanisms is an important step to develop strategies for regaining motor function after different injuries to the CNS. Plastic changes induced by activity occur both in the brain and spinal cord. This paper reviews the activity-dependent changes in the spinal cord neural circuits during both the developmental stages of the CNS and in adulthood.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.