ArticleJournal of cancer epidemiology2012
Genetic Influences on Physiological and Subjective Responses to an Aerobic Exercise Session among Sedentary Adults.
Article in Journal of cancer epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 78 citations in OpenAlex.
- Impact of a personalized versus moderate-intensity exercise prescription: a randomized controlled trial.Journal of behavioral medicine · 2017Trial
- Affect Following First Exercise Session as a Predictor of Treatment Response in Depression.The Journal of clinical psychiatry · 2016Trial
- Colorado stride (COSTRIDE): testing genetic and physiological moderators of response to an intervention to increase physical activity.The international journal of behavioral nutrition and physical activity · 2013Trial
- Personalized Lifestyle Interventions for Prevention and Treatment of Obesity-Related Cancers: A Call to Action.Cancers · 2025Article
- Affective response to physical activity as a deep phenotype in a non-randomized pilot study.Scientific reports · 2022Article
- Genetic Vulnerability to Opioid Addiction.Cold Spring Harbor perspectives in medicine · 2021Review
- Affective response to physical activity as an intermediate phenotype.Social science & medicine (1982) · 2021Article
- Physical Exercise: An Overview of Benefits From Psychological Level to Genetics and Beyond.Frontiers in physiology · 2021Review
- Perceived social integration predicts future physical activity through positive affect and spontaneous thoughts.Emotion (Washington, D.C.) · 2020Article
- Genetic Networks Underlying Natural Variation in Basal and Induced Activity Levels inG3 (Bethesda, Md.) · 2020Article
- Calcium-Sensing Receptor Gene Polymorphisms (CASRV1 and CASRV2) and the Physical Activity Level of Men in Lower Silesia, Poland.Frontiers in genetics · 2020Article
- Affective Determinants of Physical Activity: A Conceptual Framework and Narrative Review.Frontiers in psychology · 2020Review
- Genetics and the heart rate response to exercise.Cellular and molecular life sciences : CMLS · 2019Review
- Learning one's genetic risk changes physiology independent of actual genetic risk.Nature human behaviour · 2019Article
- Social and behavioral science priorities for genomic translation.Translational behavioral medicine · 2018Article
- Behavioral and Psychological Phenotyping of Physical Activity and Sedentary Behavior: Implications for Weight Management.Obesity (Silver Spring, Md.) · 2017Review
- Heritability of the affective response to exercise and its correlation to exercise behavior.Psychology of sport and exercise · 2017Article
- Characterization of the Rotating Exercise Quantification System (REQS), a novel Drosophila exercise quantification apparatus.PloS one · 2017Article
- Exercise genetics: seeking clarity from noise.BMJ open sport & exercise medicine · 2017Article
- Mice LackingFrontiers in behavioral neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Objective. To determine whether genetic variants suggested by the literature to be associated with physiology and fitness phenotypes predicted differential physiological and subjective responses to a bout of aerobic exercise among inactive but otherwise healthy adults. Method. Participants completed a 30-minute submaximal aerobic exercise session. Measures of physiological and subjective responding were taken before, during, and after exercise. 14 single nucleotide polymorphisms (SNPs) that have been previously associated with various exercise phenotypes were tested for associations with physiological and subjective response to exercise phenotypes. Results. We found that two SNPs in the FTO gene (rs8044769 and rs3751812) were related to positive affect change during exercise. Two SNPs in the CREB1 gene (rs2253206 and 2360969) were related to change in temperature during exercise and with maximal oxygen capacity (VO(2) max). The SLIT2 SNP rs1379659 and the FAM5C SNP rs1935881 were associated with norepinephrine change during exercise. Finally, the OPRM1 SNP rs1799971 was related to changes in norepinephrine, lactate, and rate of perceived exertion (RPE) during exercise. Conclusion. Genetic factors influence both physiological and subjective responses to exercise. A better understanding of genetic factors underlying physiological and subjective responses to aerobic exercise has implications for development and potential tailoring of exercise interventions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.