Evidence map›Paper›PMID 22899383›Full record

ArticleNanoscale2012

Voltage controlled nano-injection system for single-cell surgery.

R Adam Seger, Paolo Actis, Catherine Penfold, Michelle Maalouf, Boaz Vilozny, Nader Pourmand

Abstract read
In one paragraph

Article in Nanoscale, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Single molecule delivery into living cells.Nature communications · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Scanning Ion Conductance Microscopy.Chemical reviews · 2021
    Review
  13. Nanoneedle-Based Materials for Intracellular Studies.Advances in experimental medicine and biology · 2021
    Article
  14. Article
  15. Article
  16. Mitochondrial isolation: when size matters.Wellcome open research · 2020
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

R Adam SegerDepartment of Biomolecular Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Paolo Actis
Catherine Penfold
Michelle Maalouf
Boaz Vilozny
Nader Pourmand

Funding

WHOLE YEAST GENOME TRANSCRIPTIONAL AND FUNCTIONAL GENE MAPS--A FEASIBILITY STUDYP01HG000205 · NHGRI · STANFORD UNIVERSITY · PI HOWE, ROGER THOMAS, JI, HANLEE P · 1990 to 2016
$120.9M
A NEW ES CELL DELETION RESOURCE AND WILLIAMS SYNDROMEF32HG000205 · NHGRI · JACKSON LABORATORY · PI GOODWIN, NEAL C · 1999 to 1999
–
NHGRI NIH HHS F32 HG000205NHGRI NIH HHS P01-35HG000205NHGRI NIH HHS P01 HG000205
6 · The paper itself

Abstract

Manipulation and analysis of single cells is the next frontier in understanding processes that control the function and fate of cells. Herein we describe a single-cell injection platform based on nanopipettes. The system uses scanning microscopy techniques to detect cell surfaces, and voltage pulses to deliver molecules into individual cells. As a proof of concept, we injected adherent mammalian cells with fluorescent dyes.

Indexed as

ElectricityCell LineCell MembraneFibroblastsFluorescent DyesHumansMicroscopy, Electron, ScanningNanotechnologyFluorescent Dyes

Identifiers

PMID22899383
PMCPMC4406976

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.