ArticleTheranostics2012
Bioconjugated pluronic triblock-copolymer micelle-encapsulated quantum dots for targeted imaging of cancer: in vitro and in vivo studies.
Article in Theranostics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Meta-analysis of cellular toxicity for cadmium-containing quantum dots.Nature nanotechnology · 2016Pooled it
- Natural and synthetic nanovectors for cancer therapy.Nanotheranostics · 2023Review
- The Emerging Role of Ultrasonic Nanotechnology for Diagnosing and Treatment of Diseases.Frontiers in medicine · 2022Review
- Smart Nanocarriers as an Emerging Platform for Cancer Therapy: A Review.Molecules (Basel, Switzerland) · 2021Review
- Development ofPolymers · 2021Article
- An Injectable Click-Crosslinked Hydrogel that Prolongs Dexamethasone Release from Dexamethasone-Loaded Microspheres.Pharmaceutics · 2019Article
- Redox-sensitive micelles composed of disulfide-linked Pluronic-linoleic acid for enhanced anticancer efficiency of brusatol.International journal of nanomedicine · 2018Article
- Cross-Linked Micellar Spherical Nucleic Acids from Thermoresponsive Templates.Journal of the American Chemical Society · 2017Article
- Surfactant-stripped naphthalocyanines for multimodal tumor theranostics with upconversion guidance cream.Nanoscale · 2017Article
- Temperature-Sensitive Gold Nanoparticle-Coated Pluronic-PLL Nanoparticles for Drug Delivery and Chemo-Photothermal Therapy.Theranostics · 2017Article
- Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles.International journal of nanomedicine · 2017Article
- Dye-Sensitized Core/Active Shell Upconversion Nanoparticles for Optogenetics and Bioimaging Applications.ACS nano · 2016Article
- Article
- Passive tumor targeting and imaging by using mercaptosuccinic acid-coated near-infrared quantum dots.International journal of nanomedicine · 2015Article
- Echographic imaging of tumoral cells through novel nanosystems for image diagnosis.World journal of radiology · 2014Review
- Polymeric materials for theranostic applications.Pharmaceutical research · 2014Review
- Selective inhibition of liver cancer growth realized by the intrinsic toxicity of a quantum dot-lipid complex.International journal of nanomedicine · 2014Article
- Nanotheranostics - application and further development of nanomedicine strategies for advanced theranostics.Theranostics · 2014Review
- Quantum dot-based nanoprobes for in vivo targeted imaging.Current molecular medicine · 2013Review
- Synthesis of Zn-Cu-In-S/ZnS core/shell quantum dots with inhibited blue-shift photoluminescence and applications for tumor targeted bioimaging.Theranostics · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early in this study, CdTe/ZnS core/shell quantum dots (QDs) were encapsulated in carboxylated Pluronic F127 triblock polymeric micelle, to preserve the optical and colloidal stability of QDs in biological fluids. Folic acid (FA) was then conjugated to the surface of QDs for the targeted delivery of the QD formulation to the tumor site, by exploiting the overexpressed FA receptors (FARs) on the tumor cells. Cytotoxicity study demonstrated that the QD formulation has negligible in vitro toxicity. The in vitro study showed that the bioconjugated micelle-encapsulated QDs, but not the unconjugated QDs, were able to efficiently label Panc-1 cancer cells. In vivo imaging study showed that bioconjugated QDs were able to target tumor site after intravenous injection of the formulation in tumor-bearing mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.