Evidence map›Paper›PMID 22896769›Full record

ArticleTheranostics2012

Quantum dots: an insight and perspective of their biological interaction and how this relates to their relevance for clinical use.

Martin J D Clift, Vicki Stone

Abstract read
In one paragraph

Article in Theranostics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. New Generation of Photosensitizers Based on Inorganic Nanomaterials.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  5. Article
  6. Natural carbon-based quantum dots and their applications in drug delivery: A review.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Drug Carrier for Photodynamic Cancer Therapy.International journal of molecular sciences · 2015
    Review
  12. Review
  13. Targeted therapy using nanotechnology: focus on cancer.International journal of nanomedicine · 2014
    Review
  14. Article
  15. Article
  16. Article
  17. Quantum dots for biophotonics.Theranostics · 2012
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Martin J D Clift1. Bionanomaterials, Adolphe Merkle Institute, University of Fribourg, Rte de l'Ancienne Papeterie, Marly 1, 1723, Fribourg, Switzerland.
Vicki Stone

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to their novel physico-chemical characteristics, semi-conductor nanocrystal quantum dots (QDs) provide an advantageous perspective towards numerous different consumer and medical applications. The most notable potential application of QDs is their use as therapeutic and diagnostic tools in nanomedicine. Despite the many benefits posed by QDs, the proposed, intentional exposure to humans has raised concerns towards their potential impact upon human health. These concerns are predominantly based upon the heterogeneous composition of QDs, which most commonly comprises of a cadmium-based core and zinc sulphide shell. Whilst other nanoparticle (NP) types possess a similar structure to QDs (i.e. core-shell technology (e.g. Fe(2)O(3), Au and superparamagnetic iron oxide NPs)), the importance of the concerns surrounding human exposure to QDs is amplified further since, due to the sophisticated chemical and light-emitting properties of QDs, the use of these NPs within any (nano)medical setting/application could be suggested as realistic, rather than simply an advantageous possibility. It is therefore imperative that a thorough understanding of how QDs interact with various biological systems, predominantly those relative to humans and what the consequences of such interactions are is gained with extreme alacrity. It is the aim of this review to highlight the current knowledge base of QD-biological system interactions, where the knowledge gaps (still) remain and how the understanding of this interaction relates to the most notable of applications for QDs; their clinical relevance.

Indexed as

Clinical Relevance.Human Health EffectsNanocrystalsNanomedicineNanoparticlesNP-cell InteractionsQuantum dots

Identifiers

PMID22896769
PMCPMC3418927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.