ReviewPsychopharmacology2012
Nonhuman primate models of social behavior and cocaine abuse.
Review in Psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 51 citations in OpenAlex.
- Sex, social rank, and nicotine co-administration shape cocaine- and cocaethylene-induced reinstatement in monkeys.Frontiers in behavioral neuroscience · 2026Article
- Longevity and Catheter-Related Infection Rates in Nonhuman Primates with Chronic Indwelling Intravenous Catheters.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Ethanol self-administration reduced the efficacy of a behavioral intervention to decrease cocaine choice in socially housed male and female monkeys.Drug and alcohol dependence · 2025Article
- The impact of sex, species, environmental context, and alternative reinforcers in animal models of cocaine use disorders.Pharmacology, biochemistry, and behavior · 2025Review
- Punishment of ethanol choice in group-housed male cynomolgus monkeys.Drug and alcohol dependence · 2025Article
- Convergent and divergent neural and behavioral responses to chronic cocaine use in macaques.bioRxiv : the preprint server for biology · 2025Article
- Ethanol consumption prior to cocaine self-administration reduced vulnerability to cocaine reinforcement in socially subordinate female and male monkeys.Psychopharmacology · 2025Article
- A role for the insula in establishing social dominance: structural and functional MRI studies in nonhuman primates.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Selective dopamine D3 receptor partial agonist (±)VK4-40 reduces the reinforcing strength of d-amphetamine but not cocaine in rhesus monkeys responding under a progressive-ratio schedule of reinforcement.Drug and alcohol dependence · 2024Article
- Cognitive performance as a behavioral phenotype associated with cocaine self-administration in female and male socially housed monkeys.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Behavioral and neuronal extracellular vesicle biomarkers associated with nicotine's enhancement of the reinforcing strength of cocaine in female and male monkeys.Addiction neuroscience · 2024Article
- Cognitive-Enhancing Effects of Acetylcholine Receptor Agonists in Group-Housed Cynomolgus Monkeys Who Drink Ethanol.The Journal of pharmacology and experimental therapeutics · 2024Article
- Acquisition of cocaine reinforcement using fixed-ratio and concurrent choice schedules in socially housed female and male monkeys.Psychopharmacology · 2024Article
- Sex differences in dominance relationships in Syrian hamsters.Physiology & behavior · 2023Article
- Influence of social rank on the development of long-term ethanol drinking trajectories in cynomolgus monkeys.Alcohol, clinical & experimental research · 2023Article
- Delay discounting as a behavioral phenotype associated with social rank in female and male cynomolgus monkeys: Correlation with kappa opioid receptor availability.Pharmacology, biochemistry, and behavior · 2023Article
- PET imaging of kappa opioid receptors and receptor expression quantified in neuron-derived extracellular vesicles in socially housed female and male cynomolgus macaques.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Responding to the opioid crisis in North America and beyond: recommendations of the Stanford-Lancet Commission.Lancet (London, England) · 2022Review
- Social dominance in monkeys: Lack of effect on ethanol self-administration during schedule induction.Alcohol (Fayetteville, N.Y.) · 2022Article
- Social status and susceptibility to wildfire smoke among outdoor-housed female rhesus monkeys: A natural experiment.Heliyon · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
rationaleAlthough cocaine is often abused in social situations, very few animal studies examine the effects of cocaine in the context of social behavior.
objectivesThis review highlights studies investigating the behavioral effects of cocaine in the context of social housing conditions using nonhuman primates. In addition, this review presents recent findings examining the effects of self-administering cocaine on social behavior and the effects of manipulations hypothesized to be stressful or enriching on the interactions between cocaine reinforcement and social rank. The following dependent variables are examined: (1) cocaine-induced changes in social behavior and (2) cocaine self-administration in cynomolgus monkeys of varying social ranks. The independent variables examined include several environmental and pharmacological manipulations.
conclusionsThe studies reviewed here indicate that several variables can differentially affect cocaine self-administration when studied in a social context, rather than in individually housed animals. These variables include the social rank and sex of the individual, drug history, the nature of the "fear"-inducing manipulation, and the reliability of cortisol as an appropriate measure of "stress." While the inclusion of socially housed animals necessitates larger sample sizes, animal models incorporating social behavior are more homologous to the human condition and should be implemented when possible.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.