Evidence map›Paper›PMID 22895603›Full record

ReviewCirculation. Arrhythmia and electrophysiology2012

Long-QT syndrome: from genetics to management.

Peter J Schwartz, Lia Crotti, Roberto Insolia

Erratum issuedAbstract readReview
In one paragraph

Review in Circulation. Arrhythmia and electrophysiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 309 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
309citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

309 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. C-terminal long-QT type 1 R562S-Kv7.1 variant, the first variant in helix C impairing β-adrenergic response of the slow delayed rectifier K+ channel.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Channelopathy linkingJCEM case reports · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

249 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

3 authors.

Peter J SchwartzDepartment of Molecular Medicine, University of Pavia, Pavia, Italy. peter.schwartz@unipv.it
Lia Crotti
Roberto Insolia

Funding

Genetic Modifiers of Congenital Long QT SyndromeR01HL068880 · NHLBI · VANDERBILT UNIVERSITY · PI GEORGE, ALFRED L. · 2001 to 2011
$4.8M
NHLBI NIH HHS HL68880NHLBI NIH HHS R01 HL068880Telethon GGP09247
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenergic beta-AntagonistsAnimalsDefibrillators, ImplantableDNA Mutational AnalysisElectric CountershockGenetic Predisposition to DiseaseGenetic TestingGenetic TherapyHumansLong QT SyndromeMutationPhenotypePrevalenceSympathectomyAdrenergic beta-Antagonists

Identifiers

PMID22895603
PMCPMC3461497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.