ReviewNature reviews. Neuroscience2012
Distributed synergistic plasticity and cerebellar learning.
Review in Nature reviews. Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 308 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
308 citing papers in PubMed, 1 synthesis or guideline pooled it, 490 citations in OpenAlex.
- Cerebellar tDCS and pain modulation: a critical integrative and systematic review.Frontiers in neurology · 2025Pooled it
- Trial
- Purkinje Cells in Crus I and II Encode the Visual Stimulus and the Impending Choice as Monkeys Learn a Reinforcement-Based Visuomotor Association Task.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Cerebellar rhythms: mechanisms, functions and translational opportunities.Nature reviews. Neuroscience · 2026Review
- Anatomy of Cerebro-cerebellar Circuits in Motor Control.Cerebellum (London, England) · 2026Review
- Article
- Cerebellum-inspired neural network of supervised learning with tensor-based sparse coding for multi-class classification.PLoS computational biology · 2026Article
- The Cerebellar Connectome.Cerebellum (London, England) · 2026Article
- Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits.Nature neuroscience · 2026Article
- MeCP2 is Necessary in Cerebellar Purkinje Cells for Precise Network Dynamics During Associative Motor Learning.bioRxiv : the preprint server for biology · 2026Article
- Cerebellum violates Marr-Albus predictions to train synapses on long-term anticipatory goals.bioRxiv : the preprint server for biology · 2026Article
- Cerebellar contributions to action and cognition: Prediction, timescale, and continuity.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Purkinje cell intrinsic activity shapes cerebellar development and function.Nature communications · 2026Article
- Article
- Treatment with perampanel alleviates depression-like behavior in mice via modulating GluN2B expression to improve excitatory synaptic transmission.Translational psychiatry · 2026Article
- Seizures Reprogram Cerebellar Purkinje Neurons: A Multivariate Electrophysiological Classification Reveals Hidden Subtypes.Cerebellum (London, England) · 2026Article
- Filtering the noise: a cerebellar-centered framework for understanding and treating mental illness -a paradigm shift in psychiatry.Frontiers in psychiatry · 2026Article
- Deletion of Glutamate Delta 1 Receptor Leads to Heterogeneous Transcription and Synaptic Gene Alterations Across Brain Regions.International journal of molecular sciences · 2025Article
- Eye movement desensitisation and reprocessing as a potential treatment for substance use disorders: study protocol.European journal of psychotraumatology · 2025Article
- A computational model of the cerebellar granular layer calibrated to experimental data for studying inhibition and sensory encoding.Scientific reports · 2025Article
248 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies on synaptic plasticity in the context of learning have been dominated by the view that a single, particular type of plasticity forms the underlying mechanism for a particular type of learning. However, emerging evidence shows that many forms of synaptic and intrinsic plasticity at different sites are induced conjunctively during procedural memory formation in the cerebellum. Here, we review the main forms of long-term plasticity in the cerebellar cortex that underlie motor learning. We propose that the different forms of plasticity in the granular layer and the molecular layer operate synergistically in a temporally and spatially distributed manner, so as to ultimately create optimal output for behaviour.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.