Evidence map›Paper›PMID 22895251›Full record

ArticleGenes & development2012

Intercepting noncoding messages between germline and soma.

Shan Gao, Yifan Liu

Abstract readComment
In one paragraph

Article in Genes & development, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. RNAi-dependentGenes & development · 2019
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Shan GaoDepartment of Pathology, University of Michigan, Ann Arbor, Michigan 48109, USA.
Yifan Liu

Funding

Polycomb-mediated heterochromatin formation in TetrahymenaR01GM087343 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, YIFAN · 2010 to 2014
$1.4M
NIGMS NIH HHS R01 GM087343
6 · The paper itself

Abstract

There is growing evidence to support the notion that small RNAs derived from noncoding RNAs (ncRNAs) are mobile carriers of epigenetic information in diverse eukaryotic systems. However, challenges remain in defining what messages are being sent and how. In the August 1, 2012, issue of Genes & Development, Schoeberl and colleagues (pp. 1729-1742) reported a detailed analysis of the turnover of small RNAs during the sexual reproduction of the ciliated protozoan Tetrahymena. The results revealed surprisingly complicated roles played by small RNAs in shaping the communication between the germline and the soma.

Indexed as

RNA StabilityTranscription, GeneticDNA, ProtozoanRNA, ProtozoanRNA, Small InterferingTetrahymenaDNA, ProtozoanRNA, ProtozoanRNA, Small Interfering

Identifiers

PMID22895251
PMCPMC3426757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.