ArticleHuman vaccines & immunotherapeutics2012
House dust allergy and immunotherapy.
Article in Human vaccines & immunotherapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Article
- Analysis of the characteristics of blood inflammatory cytokines and their influencing factors in acute exacerbations of allergic asthma in children.Frontiers in pediatrics · 2025Article
- Prevalence, symptomatology and factors associated with asthma in adolescents aged 13-14 years from rural Sri Lanka: an analytical cross-sectional study.BMJ paediatrics open · 2024Article
- Identification of an immunodominant IgE epitope of Der f 40, a novel allergen ofThe World Allergy Organization journal · 2023Article
- Combined application of dinitrofluorobenzene and ovalbumin induced AD-like dermatitis with an increase in helper T-cell cytokines and a prolonged Th2 response.BMC immunology · 2022Article
- Caspase-11 regulates lung inflammation in response to house dust mites.Cellular immunology · 2021Article
- Insights Into Mucosal Innate Immune Responses in House Dust Mite-Mediated Allergic Asthma.Frontiers in immunology · 2020Review
- Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection.Scientific reports · 2019Article
- Identification of immunodominant IgE binding epitopes of Der p 24, a major allergen ofClinical and translational allergy · 2019Article
- Cross-sectional study on sensitization to mite and cockroach allergen components in allergy patients in the Central European region.Clinical and translational allergy · 2018Article
- Allergens with Protease Activity from House Dust Mites.International journal of molecular sciences · 2017Review
- Immunotherapeutic efficacy of liposome-encapsulated refined allergen vaccines against Dermatophagoides pteronyssinus allergy.PloS one · 2017Article
- House Dust Mite Allergens: New Discoveries and Relevance to the Allergic Patient.Current allergy and asthma reports · 2016Review
- Indoor Allergens and Allergic Respiratory Disease.Current allergy and asthma reports · 2016Review
- Debates in allergy medicine: specific immunotherapy efficiency in children with atopic dermatitis.The World Allergy Organization journal · 2016Article
- Construction of the recombinant vaccine based on T-cell epitope encoding Der p1 and evaluation on its specific immunotherapy efficacy.International journal of clinical and experimental medicine · 2015Article
- The effects of storage conditions on the stability of house dust mite extracts.Allergy, asthma & immunology research · 2013Article
- Allergen-specific IgG antibodies purified from mite-allergic patients sera block the IgE recognition of Dermatophagoides pteronyssinus antigens: an in vitro study.Clinical & developmental immunology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis. In many countries childhood asthma is predominantly found in HDM-allergic children with their probability of developing disease being proportional to their IgE antibody titers and the early development of Th2 responses. While the pathogenesis is complex and increasingly linked to infection the immunologically-based allergen immunotherapy and anti-IgE antibody therapy are highly beneficial. Immunotherapy could be a short-term treatment providing lifelong relief but the current regimens depend on repeated administration of allergen over years. Immunological investigations point to a contribution of responses outside the Th2 pathway and multiple potential but unproven control mechanisms. Over half of the IgE antibodies are directed to the group 1 and 2 allergens with most of remainder to the group 4, 5, 7 and 21 allergens. This hierarchy found in high and low responders provides a platform for introducing defined allergens into immunotherapy and defined reagents for investigation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.