ArticleThe Journal of general virology2012
Apoptosis in mosquito salivary glands: Sindbis virus-associated and tissue homeostasis.
Article in The Journal of general virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Susceptibility of Aedes albopictus, Ae. aegypti and human populations to Ross River virus in Kuala Lumpur, Malaysia.PLoS neglected tropical diseases · 2023Article
- Evaluating the mosquito host range of Getah virus and the vector competence of selected medically important mosquitoes in Getah virus transmission.Parasites & vectors · 2023Article
- The Role of Mosquito Hemocytes in Viral Infections.Viruses · 2022Review
- Review
- Apoptosis in a Whitefly Vector Activated by a Begomovirus Enhances Viral Transmission.mSystems · 2020Article
- A Hyperactive Kunjin Virus NS3 Helicase Mutant Demonstrates Increased Dissemination and Mortality in Mosquitoes.Journal of virology · 2020Article
- JNK pathway restricts DENV2, ZIKV and CHIKV infection by activating complement and apoptosis in mosquito salivary glands.PLoS pathogens · 2020Article
- Reproducibility and relevance in insect-arbovirus infection studies.Current opinion in insect science · 2018Review
- Vector competence and innate immune responses to dengue virus infection in selected laboratory and field-collected Stegomyia aegypti (= Aedes aegypti).Medical and veterinary entomology · 2017Article
- Filamentous Structures Induced by a Phytoreovirus Mediate Viral Release from Salivary Glands in Its Insect Vector.Journal of virology · 2017Article
- Apoptosis-related genes control autophagy and influence DENV-2 infection in the mosquito vector, Aedes aegypti.Insect biochemistry and molecular biology · 2016Article
- Arboviruses and apoptosis: the role of cell death in determining vector competence.The Journal of general virology · 2016Review
- Infection pattern and transmission potential of chikungunya virus in two New World laboratory-adapted Aedes aegypti strains.Scientific reports · 2016Article
- Tissue Barriers to Arbovirus Infection in Mosquitoes.Viruses · 2015Review
- Rice ragged stunt virus-induced apoptosis affects virus transmission from its insect vector, the brown planthopper to the rice plant.Scientific reports · 2015Article
- Rapid selection against arbovirus-induced apoptosis during infection of a mosquito vector.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Heparan sulfate proteoglycan: an arbovirus attachment factor integral to mosquito salivary gland ducts.Viruses · 2014Article
- Eilat virus displays a narrow mosquito vector range.Parasites & vectors · 2014Article
- Infection with dengue-2 virus alters proteins in naturally expectorated saliva of Aedes aegypti mosquitoes.Parasites & vectors · 2014Article
- Complement-related proteins control the flavivirus infection of Aedes aegypti by inducing antimicrobial peptides.PLoS pathogens · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Apoptosis is observed during a spectrum of conditions including exogenous virus infection and endogenous cellular turnover. Adult female Aedes albopictus mosquitoes challenged with increasing titres of Sindbis virus (SINV) via intrathoracic inoculation demonstrated that the injection dosage did not result in significantly different levels of virus growth or mosquito survival at day 10 post-infection. Tissues probed for apoptosis using an in situ TUNEL assay revealed SINV-associated apoptotic cells scattered throughout the proximal and distal regions of the salivary gland (SG) lateral lobes but which were not detected in the median lobe or the midgut and hindgut. Apoptosis was also identified in SG duct cells in both infected and uninfected mosquitoes, suggesting routine tissue homeostasis. SINV-associated apoptosis sequestered to the SG lateral lobes indicates a differential epithelial cell response to an arbovirus and provides insight into mosquito defence mechanisms against pathogens and SG infection barriers, hurdles to transmission of arboviruses of public health concern.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.