ArticleHybridoma (2005)2012
Monoclonal antibodies to DIPA: a novel binding partner of p120-catenin isoform 1.
Article in Hybridoma (2005), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Differential expression of p120-catenin 1 and 3 isoforms in epithelial tissues.Scientific reports · 2019Article
- MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation.Current biology : CB · 2016Article
- Phosphorylation and isoform use in p120-catenin during development and tumorigenesis.Biochimica et biophysica acta · 2016Review
- Kinetics of lung tissue factor expression and procoagulant activity in bleomycin induced acute lung injury.Clinical and translational medicine · 2015Article
- Regulation of alveolar procoagulant activity and permeability in direct acute lung injury by lung epithelial tissue factor.American journal of respiratory cell and molecular biology · 2015Article
- An instructive role for C. elegans E-cadherin in translating cell contact cues into cortical polarity.Nature cell biology · 2015Article
- ANTI-MTG16 ANTIBODIES REVEAL MTG16 SUBCELLULAR DISTRIBUTION AND NUCLEOCYTOPLASMIC TRANSPORT IN ERYTHROLEUKEMIA CELLS.Antibody technology journal · 2015Article
- DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.Molecular biology of the cell · 2014Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The coiled-coil domain-containing delta-interacting protein A (DIPA) is a transcription factor implicated in developmental regulation. DIPA is the first protein discovered to selectively interact with the p120-catenin (p120) isoform 1, an alternatively spliced form of p120 expressed preferentially in mesenchymal cells. Although a small fraction of p120 can be observed in the nucleus under certain circumstances, the vast majority of it associates with classical cadherins at adherens junctions. We observed for the first time that a discrete fraction of DIPA exists at cell-cell junctions, in addition to its predominantly nuclear localization. Thus, the p120-DIPA interaction may regulate cell signaling and/or transcriptional events, as has been described previously for β-catenin and the LEF/TCF transcription factor family. To facilitate further study of DIPA and to determine the physiological relevance of its interaction with p120, we have generated and characterized a panel of five DIPA-specific monoclonal antibodies (MAbs) that function in immunoblotting, immunoprecipitation, and immunofluorescence assays.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.