ArticleOrganic letters2012
Stereoselective synthesis of morpholines via copper-promoted oxyamination of alkenes.
Article in Organic letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 91 citations in OpenAlex.
- Asymmetric hydrogenation for the synthesis of 2-substituted chiral morpholines.Chemical science · 2021Article
- Copper-Promoted Conjugate Addition of Carboxylic Acids to Ethenesulfonyl Fluoride (ESF) for Constructing Aliphatic Sulfonyl Fluorides.ACS omega · 2021Article
- Copper-catalyzed enantioselective alkene carboetherification for the synthesis of saturated six-membered cyclic ethers.Chemical communications (Cambridge, England) · 2021Article
- Enantio- and Regioselective Palladium(II)-Catalyzed Dioxygenation of (Aza-)Alkenols.Angewandte Chemie (International ed. in English) · 2021Article
- Halonium Catalysis: An Underutilized and Underexplored Catalytic Concept in Olefin Functionalizations.Synlett : accounts and rapid communications in synthetic organic chemistry · 2021Article
- Copper-catalyzed enantioselective synthesis of bridged bicyclic ketals from 1,1-disubstituted-4-methylene-1,6-hexanediols and related alkenols.Chemical communications (Cambridge, England) · 2021Article
- Efficient Stereoselective Carbocyclization toJournal of the American Chemical Society · 2020Article
- Selenophosphoramide-catalyzed diamination and oxyamination of alkenes.Chemical science · 2020Article
- Ligand Controlled Ir-Catalyzed Regiodivergent Oxyamination of Unactivated Alkenes.Journal of the American Chemical Society · 2019Article
- Stereoselective and Regioselective Synthesis of Heterocycles via Copper-Catalyzed Additions of Amine Derivatives and Alcohols to Alkenes.The Journal of organic chemistry · 2017Article
- Practical Synthetic Procedures for the Iron-Catalyzed Intermolecular Olefin Aminohydroxylation Using Functionalized Hydroxylamines.Synthesis · 2016Article
- Azidation in the Difunctionalization of Olefins.Molecules (Basel, Switzerland) · 2016Review
- Catalytic, Stereoselective Dihalogenation of Alkenes: Challenges and Opportunities.Angewandte Chemie (International ed. in English) · 2015Review
- Copper(II)-Promoted Cyclization/Difunctionalization of Allenols and Allenylsulfonamides: Synthesis of Heterocycle-Functionalized Vinyl Carboxylate Esters.Organic letters · 2015Article
- Versatile Enantioselective Synthesis of Functionalized Lactones via Copper-Catalyzed Radical Oxyfunctionalization of Alkenes.Journal of the American Chemical Society · 2015Article
- Copper-catalyzed aminooxygenation of styrenes with N-fluorobenzenesulfonimide and N-hydroxyphthalimide derivatives.Beilstein journal of organic chemistry · 2015Article
- Iron(II)-catalyzed intermolecular amino-oxygenation of olefins through the N-O bond cleavage of functionalized hydroxylamines.Journal of the American Chemical Society · 2014Article
- Copper-catalyzed oxidative Heck reactions between alkyltrifluoroborates and vinyl arenes.Organic letters · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A new copper(II) 2-ethylhexanoate-promoted addition of an alcohol and an amine across an alkene (oxyamination) is reported. The alcohol addition is intramolecular, while coupling with the amine occurs intermolecularly. Several 2-aminomethyl morpholines were synthesized in good to excellent yields and diastereoselectivities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.