Evidence map›Paper›PMID 22894576›Full record

ArticleThe New England journal of medicine2012

Franklin H. Epstein Lecture. Both ends of the leash--the human links to good dogs with bad genes.

Elaine A Ostrander

Open access · bronzeAbstract readLecture
In one paragraph

Article in The New England journal of medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Canine models of inherited retinal diseases: from neglect to well-recognized translational value.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Shape of the Nasal Cavity and Adaptations to Sniffing in the Dog (Animals : an open access journal from MDPI · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. A scan for genes associated with cancer mortality and longevity in pedigree dog breeds.Mammalian genome : official journal of the International Mammalian Genome Society · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Innovative approaches in cognitive aging.Neurobiology of aging · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Elaine A OstranderNational Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA. eostrand@mail.nih.gov
National Human Genome Research Institute · US

Funding

Comparative Mammalian GenomicsZIAHG200377 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI OSTRANDER, ELAINE · 2012 to 2025
$24.8M
Intramural NIH HHS ZIA HG200377
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chromosome MappingGenomeAnimalsBehavior, AnimalBreedingDog DiseasesDogsGenetic VariationGenome, HumanGenomicsHumansLinkage DisequilibriumMultigene FamilyNeoplasmsPedigreePhenotype

Identifiers

PMID22894576
PMCPMC3508784
OpenAlexW2051441964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.