Evidence map›Paper›PMID 22894472›Full record

ReviewJournal of biomedical optics2012

Diffuse optical imaging using spatially and temporally modulated light.

Thomas D O'Sullivan, Albert E Cerussi, David J Cuccia, Bruce J Tromberg

Abstract readReview
In one paragraph

Review in Journal of biomedical optics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. Review
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  7. Review
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  16. Phase-based structured interrogation frequency-domain near-infrared spectroscopy.Journal of the Optical Society of America. A, Optics, image science, and vision · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas D O'SullivanUniversity of California, Irvine, Laser Microbeam and Medical Program (LAMMP), Beckman Laser Institute and Medical Clinic, Irvine, California, USA.
Albert E Cerussi
David J Cuccia
Bruce J Tromberg

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
WOUND MIGRATION FORCE MONITORINGP41RR001192 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI LYUBOVITSKY, JULIA · 1985 to 2011
$14.2M
CARCINOGENESIST32CA009054 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI EDINGER, AIMEE L, FRUMAN, DAVID ALEXANDER · 1985 to 2025
$8.6M
Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY J · 2012 to 2017
$7.0M
SPATIAL /SPECTRAL TOMOGRAPHY FOR FUNCTIONAL SPECTROSCOPYU54CA105480 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI TROMBERG, BRUCE J · 2003 to 2007
$6.6M
Developing DOSI Technology for Monitoring Response To Breast Cancer ChemotherapyR01CA142989 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY J · 2010 to 2017
$4.1M
Monitoring Breast Cancer Chemotherapeutic Response Using DOSI, MRI and BiomarkersU54CA136400 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI TROMBERG, BRUCE J. · 2009 to 2011
$1.3M
PHOTODYNAMIC TREATMENT OF BENIGN UTERINE DISEASER01HD034091 · NICHD · UNIVERSITY OF CALIFORNIA IRVINE · PI TROMBERG, BRUCE J · 1998 to 2000
$183k
NCI NIH HHS NCI-2P30CA62203NCI NIH HHS NCI-T32CA009054NCI NIH HHS P30 CA062203NCI NIH HHS R01 CA142989NCI NIH HHS R01-CA142989NCI NIH HHS T32 CA009054NCI NIH HHS U54 CA105480NCI NIH HHS U54-CA105480NCI NIH HHS U54 CA136400NCI NIH HHS U54-CA136400NCRR NIH HHS P41 RR001192NCRR NIH HHS P41RR01192NIBIB NIH HHS P41 EB015890NIBIB NIH HHS P41EB015890NICHD NIH HHS R01 HD034091
6 · The paper itself

Abstract

The authors describe the development of diffuse optical imaging (DOI) technologies, specifically the use of spatial and temporal modulation to control near infrared light propagation in thick tissues. We present theory and methods of DOI focusing on model-based techniques for quantitative, in vivo measurements of endogenous tissue absorption and scattering properties. We specifically emphasize the common conceptual framework of the scalar photon density wave for both temporal and spatial frequency-domain approaches. After presenting the history, theoretical foundation, and instrumentation related to these methods, we provide a brief review of clinical and preclinical applications from our research as well as our outlook on the future of DOI technology.

Indexed as

Equipment DesignImage EnhancementLightingOptical Imaging

Identifiers

PMID22894472
PMCPMC3607494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.