Evidence map›Paper›PMID 22893765›Full record

Trial reportJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2012

Exercise training improves selected aspects of daytime functioning in adults with obstructive sleep apnea.

Christopher E Kline, Gary B Ewing, James B Burch, Steven N Blair, J Larry Durstine, J Mark Davis, Shawn D Youngstedt

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 6 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 6 syntheses or guidelines pooled it, 76 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christopher E KlineDepartment of Psychiatry, University of Pittsburgh School of Medicine, 3811 O’Hara Street, Pittsburgh, PA 15213, United States. klinec@upmc.edu
Gary B Ewing
James B Burch
Steven N Blair
J Larry Durstine
J Mark Davis
Shawn D Youngstedt
University of South Carolina · USUniversity of Pittsburgh · US

Funding

Translational Research Training in Sleep MedicineT32HL082610 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Daniel J. Buysse, PETER L FRANZEN · 2007 to 2026
$5.8M
Exercise: A Novel Treatment for Obstructive Sleep ApneaR36CD000695 · CD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KLINE, CHRISTOPHER EDWARD · 2008 to 2008
$38k
NHLBI NIH HHS T32 HL082610ODCDC CDC HHS 1R36CD000695-1ODCDC CDC HHS R36 CD000695
6 · The paper itself

Abstract

STUDY

objectivesTo explore the utility of exercise training for improving daytime functioning in adults with obstructive sleep apnea (OSA).

methodsForty-three sedentary and overweight/obese adults aged 18-55 years with at least moderate-severity untreated OSA (apnea-hypopnea index ≥ 15) were randomized to 12 weeks of moderate-intensity aerobic and resistance exercise training (n = 27) or low-intensity stretching control treatment (n = 16). As part of a trial investigating the efficacy of exercise training on OSA severity, daytime functioning was assessed before and following the intervention. Sleepiness, functional impairment due to sleepiness, depressive symptoms, mood, and quality of life (QOL) were evaluated with validated questionnaires, and cognitive function was assessed with a neurobehavioral performance battery. OSA severity was measured with one night of laboratory polysomnography before and following the intervention.

resultsCompared with stretching control, exercise training resulted in significant improvements in depressive symptoms, fatigue and vigor, and aspects of QOL (p < 0.05). Sleepiness and functional impairment due to sleepiness also were improved following exercise versus control to a similar degree in terms of effect sizes (d > 0.5), though these changes were not statistically significant. No neurobehavioral performance improvements were found. Reduced fatigue following exercise training was mediated by a reduction in OSA severity, but changes in OSA severity did not significantly mediate improvement in any other measure of daytime functioning.

conclusionsThese data provide preliminary evidence that exercise training may be helpful for improving aspects of daytime functioning of adults with OSA. Larger trials are needed to further verify the observed improvements.

Indexed as

Exercise TherapyWakefulnessActivities of Daily LivingAdolescentAdultDepressionExerciseFemaleHumansMaleMiddle AgedNeuropsychological TestsPolysomnographyQuality of LifeResistance TrainingSeverity of Illness Indexcognitive performanceexercise trainingmoodobstructive sleep apneaquality of lifesleepiness

Identifiers

PMID22893765
PMCPMC3407253
OpenAlexW1972401688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.