ArticleApplied physics letters2012
High-resolution imaging in a deep turbid medium based on an ultrasound-switchable fluorescence technique.
Article in Applied physics letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Improving the spatial resolution and signal-to-noise ratio of ultrasound switchable fluorescence imaging.Journal of biophotonics · 2024Article
- Fast ICCD-based temperature modulated fluorescence tomography.Applied optics · 2023Article
- Noninvasive measurement of local temperature using ultrasound-switchable fluorescence.Biomedical optics express · 2023Article
- Size effect of liposomes on centimeter-deep ultrasound-switchable fluorescence imaging and ultrasound-controlled release.Journal of materials chemistry. B · 2022Article
- Development of a preclinical CCD-based temperature modulated fluorescence tomography platform.Biomedical optics express · 2022Article
- Interstitial fluid streaming in deep tissue induced by ultrasound momentum transfer for accelerating nanoagent transport and controlling its distribution.Physics in medicine and biology · 2022Article
- Recent advances in ultrasound-controlled fluorescence technology for deep tissue optical imaging.Journal of pharmaceutical analysis · 2022Review
- Fluorescent Phase-Changing Perfluorocarbon Nanodroplets as Activatable Near-Infrared Probes.International journal of molecular sciences · 2022Article
- Improving sensitivity and imaging depth of ultrasound-switchable fluorescence via an EMCCD-gain-controlled system and a liposome-based contrast agent.Quantitative imaging in medicine and surgery · 2021Article
- Article
- A Personal Journey across Fluorescent Sensing and Logic Associated with Polymers of Various Kinds.Polymers · 2019Review
- An ICCD camera-based time-domain ultrasound-switchable fluorescence imaging system.Scientific reports · 2019Article
- In vivo ultrasound-switchable fluorescence imaging.Scientific reports · 2019Article
- Newly-Engineered Materials for Bio-Imaging Technology: A Focus on the Hybrid System of Ultrasound and Fluorescence.Frontiers in bioengineering and biotechnology · 2019Review
- Nanomedicines for Near-Infrared Fluorescent Lifetime-Based Bioimaging.Frontiers in bioengineering and biotechnology · 2019Review
- The Mechanisms and Biomedical Applications of an NIR BODIPY-Based Switchable Fluorescent Probe.International journal of molecular sciences · 2017Article
- A Dual-Modality System for Both Multi-Color Ultrasound-Switchable Fluorescence and Ultrasound Imaging.International journal of molecular sciences · 2017Article
- Experimental evaluation of the resolution and quantitative accuracy of temperature-modulated fluorescence tomography.Applied optics · 2017Article
- New generation ICG-based contrast agents for ultrasound-switchable fluorescence imaging.Scientific reports · 2016Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The spatial resolution of fluorescence imaging techniques in deep optically turbid media such as tissues is limited by photon diffusion. To break the diffusion limit and achieve high-resolution and deep-tissue fluorescence imaging, a fundamentally different method was demonstrated based on a concept of ultrasound-switchable fluorescence. The results showed that a small fluorescent tube with a diameter of ∼180 μm at a depth of ∼20 mm in an optical scattering medium ([Formula: see text] and [Formula: see text] cm(-1)) can be clearly imaged with a size of ∼260 μm. The depth-to-resolution ratio is shown to be about one order of magnitude better than other deep-tissue fluorescence imaging techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.