Evidence map›Paper›PMID 22893360›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2013

Orthostatic hypotension, non-dipping and striatal dopamine in Parkinson disease.

Yoon-Sang Oh, Joong-Seok Kim, Yong-An Chung, Ie Ryung You, Dong-Won Yang, Sung-Woo Chung, Jeong-Wook Park, Yeong-In Kim, Kwang-Soo Lee

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yoon-Sang OhDepartment of Neurology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Joong-Seok Kim
Yong-An Chung
Ie Ryung You
Dong-Won Yang
Sung-Woo Chung
Jeong-Wook Park
Yeong-In Kim
Kwang-Soo Lee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthostatic hypotension and non-dipping are relatively common autonomic dysfunctions in patients with Parkinson disease (PD). These abnormalities have been thought to occur independently of striatal dopaminergic depletion; however, only little preliminary information is available. In this study, we investigated the association of neurocirculatory changes with striatal dopamine transporter status in 69 patients with early PD. Seventeen patients had orthostatic hypotension and 55 patients were non-dippers. A comparison between cases with and without orthostatic hypotension was insignificant for striatal dopamine transporter uptake. These insignificances continued in a comparison of dippers and non-dippers. These results suggest that sympathetic noradrenergic dysfunctions in PD are independent of striatal dopamine transporter depletion.

Indexed as

AgedBlood PressureChi-Square DistributionCorpus StriatumDopamineFemaleHead MovementsHumansHypotension, OrthostaticMaleMiddle AgedParkinson DiseasePositron-Emission TomographyTilt-Table TestTomography, X-Ray ComputedTropanes2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropaneDopamineTropanes

Identifiers

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Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.