Evidence map›Paper›PMID 22892589›Full record

ArticleBioengineered

Nitrogen and sulfur deprivation differentiate lipid accumulation targets of Chlamydomonas reinhardtii.

Turgay Cakmak, Pinar Angun, Alper D Ozkan, Zeynep Cakmak, Tolga T Olmez, Turgay Tekinay

Abstract read
In one paragraph

Article in Bioengineered. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Turgay CakmakLaboratory of Sustainable Technologies; UNAM Institute of Materials Science and Nanotechnology, Bilkent University, Ankara, Turkey.
Pinar Angun
Alper D Ozkan
Zeynep Cakmak
Tolga T Olmez
Turgay Tekinay

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrogen (N) and sulfur (S) have inter-related and distinct impacts on microalgal metabolism; with N starvation having previously been reported to induce elevated levels of the biodiesel feedstock material triacylglycerol (TAG), while S deprivation is extensively studied for its effects on biohydrogen production in microalgae. ( 1) (,) ( 2) We have previously demonstrated that N- and S-starved cells of Chlamydomonas reinhardtii display different metabolic trends, suggesting that different response mechanisms exist to compensate for the absence of those two elements. ( 3) We used C. reinhardtii CC-124 mt(-) and CC-125 mt(+) strains to test possible metabolic changes related to TAG accumulation in response to N and S deprivation, considering that gamete differentiation in this organism is mainly regulated by N. ( 4) Our findings contribute to the understanding of microalgal response to element deprivation and potential use of element deprivation for biodiesel feedstock production using microalgae, but much remains to be elucidated on the precise contribution of both N and S starvation on microalgal metabolism.

Indexed as

BiofuelsCarotenoidsChlamydomonas reinhardtiiChlorophyllLipid MetabolismMicroalgaeMicroscopy, Electron, TransmissionMicroscopy, FluorescenceMutationNitrogenPhotosynthesisPlant ProteinsStarchSulfurTriglyceridesBiofuelsCarotenoidsChlorophyllNitrogenPlant ProteinsStarchSulfurTriglycerides

Identifiers

PMID22892589
PMCPMC3489711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.