Evidence map›Paper›PMID 22891869›Full record

ArticleAddiction (Abingdon, England)2013

Effectiveness of stop-smoking medications: findings from the International Tobacco Control (ITC) Four Country Survey.

Karin A Kasza, Andrew J Hyland, Ron Borland, Ann D McNeill, Maansi Bansal-Travers, Brian V Fix, David Hammond, Geoffrey T Fong, K Michael Cummings

2 registry-linked trialsOpen access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Addiction (Abingdon, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02491086 nacompletednot on this mapstarted 2015, after this paper: background citation

Motivating Smokers at Outdoor Public Smoking Hotspots to Have Quit Attempt With Nicotine Replacement Therapy Sampling: A Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2015 to 2016Enrolled100ConditionsSmoking CessationArmsNicotine replacement therapy (NRT) sampling, Smoking cessation counseling
NCT03717051 nacompletednot on this mapstarted 2018, after this paper: background citation

Use of Nicotine Replacement Therapy (NRT) Sample and Brief Smoking Cessation Advice for Recruiting Smokers to Smoking Cessation Services and Motivating Quit Attempts

TypeinterventionalSponsorThe University of Hong KongRan2018 to 2020Enrolled834ConditionsSmoking CessationArmsNicotine replacement therapy (NRT) sampling, Medication counseling
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Nicotine replacement therapy versus control for smoking cessation.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Can We Predict Who Will Experience Adverse Events While Using Smoking Cessation Pharmacotherapy? A Secondary Analysis of the EAGLES Clinical Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Karin A KaszaDivision of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. karin.kasza@roswellpark.org
Andrew J Hyland
Ron Borland
Ann D McNeill
Maansi Bansal-Travers
Brian V Fix
David Hammond
Geoffrey T Fong
K Michael Cummings
Roswell Park Comprehensive Cancer Center · USMUSC Hollings Cancer Center · USOntario Institute for Cancer Research · CAUniversity of Nottingham · GBUniversity of Waterloo · CAVictorian Health Promotion Foundation · AU

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CANDACE S JOHNSON · 1985 to 2026
$116.6M
Variation in Cigarettes, Tobacco use Behaviors and Exposures in ITC CountriesP01CA138389 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI FONG, GEOFFREY T · 2009 to 2013
$13.4M
Project 3: Policy Effects on Cigarette Design, Emissions &BehaviorP50CA111236 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CUMMINGS, KENNETH MICHAEL · 2004 to 2009
$8.2M
International Tobacco Policy SurveyR01CA100362 · NCI · UNIVERSITY OF WATERLOO · PI FONG, GEOFFREY T · 2005 to 2013
$4.7M
Tobacco Control Policy Evaluation in China and South Korea: The ITC Asia ProjectR01CA125116 · NCI · UNIVERSITY OF WATERLOO · PI FONG, GEOFFREY T · 2007 to 2011
$2.8M
Cancer Research UK C312/A11039Cancer Research UK C312/A3726Cancer Research UK C312/A6465CIHR 115016CIHR 57897CIHR 79551Medical Research CouncilNCI NIH HHS P01 CA138389NCI NIH HHS P30 CA016056NCI NIH HHS P50 CA111236NCI NIH HHS P50 CA111326NCI NIH HHS R01 CA100362NCI NIH HHS R01 CA125116
6 · The paper itself

Abstract

aimTo evaluate the population effectiveness of stop-smoking medications while accounting for potential recall bias by controlling for quit attempt recency.

designProspective cohort survey.

settingUnited Kingdom, Canada, Australia and the United States.

participantsA total of 7436 adult smokers (18+ years) selected via random digit dialling and interviewed as part of the International Tobacco Control Four Country Survey (ITC-4) between 2002 and 2009. Primary analyses utilized the subset of respondents who participated in 2006 or later (n = 2550). MEASUREMENTS: Continuous abstinence from smoking for 1 month/6 months.

findingsAmong participants who recalled making a quit attempt within 1 month of interview, those who reported using varenicline, bupropion or nicotine patch were more likely to maintain 6-month continuous abstinence from smoking compared to those who attempted to quit without medication [adjusted odds ratio (OR) 5.84, 95% confidence interval (CI) (2.12-16.12), 3.94 (0.87-17.80), 4.09 (1.72-9.74), respectively]; there were no clear effects for oral NRT use. Those who did not use any medication when attempting to quit tended to be younger, to be racial/ethnic minorities, to have lower incomes and to believe that medications do not make quitting easier.

conclusionsConsistent with evidence from randomized controlled trials, smokers in the United Kingdom, Canada, Australia and the United States are more likely to succeed in quit attempts if they use varenicline, bupropion or nicotine patch. Previous population studies that failed to find an effect failed to control adequately for important sources of bias.

Indexed as

Tobacco Use Cessation DevicesAdolescentAdultAgedAge DistributionAustraliaBenzazepinesBupropionCanadaDopamine Uptake InhibitorsFemaleHumansMaleMiddle AgedNicotinic AgonistsProspective StudiesBenzazepinesBupropionDopamine Uptake InhibitorsNicotinic AgonistsQuinoxalinesVarenicline

Identifiers

PMID22891869
PMCPMC3500450
OpenAlexW1571169387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.