Evidence map›Paper›PMID 22891735›Full record

GuidelineCongenital heart disease

Nutrition algorithms for infants with hypoplastic left heart syndrome; birth through the first interstage period.

Julie Slicker, David A Hehir, Megan Horsley, Jessica Monczka, Kenan W Stern, Brandis Roman, Elena C Ocampo, Liz Flanagan, Erin Keenan, Linda M Lambert and 6 more

Registry-linked trialOpen access · greenAbstract readPractice GuidelineReview
In one paragraph

Guideline in Congenital heart disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02657629 (Comparison of Feeding Strategies After Stage 1 Procedures for Hypoplastic Left Heart Syndrome Infants), which is not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02657629 nacompletednot on this map

Comparison of Feeding Strategies After Stage 1 Procedures for Hypoplastic Left Heart Syndrome Infants: A Randomized Controlled Trial

TypeinterventionalSponsorColumbia UniversityRan2009 to 2012Enrolled28ConditionsHypoplastic Left Heart Syndrome, Growth FailureArmsContinuous Feeding Regimen, Intermittent Bolus Feeding Regimen
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Improving preoperative enteral feeding for newborns with congenital heart disease.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 1 country.

Julie SlickerClinical Nutrition, Children's Hospital of Wisconsin, Milwaukee, WI 53201, USA. jslicker@chw.org
David A Hehir
Megan Horsley
Jessica Monczka
Kenan W Stern
Brandis Roman
Elena C Ocampo
Liz Flanagan
Erin Keenan
Linda M Lambert
Denise Davis
Marcy Lamonica
Nancy Rollison
Haleh Heydarian
Jeffrey B Anderson
Feeding Work Group of the National Pediatric Cardiology Quality Improvement Collaborative
Boston Children's Hospital · USCincinnati Children's Hospital Medical Center · USArnold Palmer Hospital for Children · USBaylor College of Medicine · USChildren's Hospital of Wisconsin · USCleveland Clinic · USMedical College of Wisconsin · USPhoenix Children's Hospital · USPrimary Children's Hospital · USUniversity of Virginia · USYale University · US

Funding

RESEARCH METHODS IN PEDIATRICS HEART DISEASET32HL007572 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI Sarah D DE FERRANTI, Jane W. Newburger · 1985 to 2026
$13.0M
Clincal and Translational Science AwardUL1TR000055 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2012 to 2015
$11.3M
NCATS NIH HHS UL1 TR000055NHLBI NIH HHS T32 HL007572
6 · The paper itself

Abstract

Failure to thrive is common in infants with hypoplastic left heart syndrome and its variants and those with poor growth may be at risk for worse surgical and neurodevelopmental outcomes. The etiology of growth failure in this population is multifactorial and complex, but may be impacted by nutritional intervention. There are no consensus guidelines outlining best practices for nutritional monitoring and intervention in this group of infants. The Feeding Work Group of the National Pediatric Cardiology Quality Improvement Collaborative performed a literature review and assessment of best nutrition practices from centers participating in the collaborative in order to provide nutritional recommendations and levels of evidence for those caring for infants with single ventricle physiology.

Indexed as

AlgorithmsCardiac Surgical ProceduresInfant Nutritional Physiological PhenomenaNutritional StatusAge FactorsConsensusDelphi TechniqueFailure to ThriveHumansHypoplastic Left Heart SyndromeInfantInfant, NewbornNutritional SupportTreatment Outcome

Identifiers

PMID22891735
PMCPMC3618624
OpenAlexW1552296198

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.