ArticleProceedings of the National Academy of Sciences of the United States of America2012
Paleontological and developmental evidence resolve the homology and dual embryonic origin of a mammalian skull bone, the interparietal.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed, 97 citations in OpenAlex.
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- Evolution of accessory bones in cetacean skull coupled with decreasing rate of ossification of cranial sutures.Scientific reports · 2025Article
- A Novel Approach to Study Cranial Shape in Children with Normal and Sagittal Synostosis: An Application of Geometric Morphometrics.Neurologia medico-chirurgica · 2025Article
- Divergent patterns of cranial suture fusion in marsupial and placental mammals.Zoological journal of the Linnean Society · 2025Article
- Variation and Variability in Skeletal Ossification of the Gray Short-tailed Opossum,Integrative organismal biology (Oxford, England) · 2024Article
- Craniofacial developmental biology in the single-cell era.Development (Cambridge, England) · 2023Review
- Evolution and development of the cetacean skull roof: a case study in novelty and homology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Craniodental anatomy in Permian-Jurassic Cynodontia and Mammaliaformes (Synapsida, Therapsida) as a gateway to defining mammalian soft tissue and behavioural traits.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Evolution, conservatism and overlooked homologies of the mammalian skull.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Gene regulatory network from cranial neural crest cells to osteoblast differentiation and calvarial bone development.Cellular and molecular life sciences : CMLS · 2022Review
- New Skull Material ofJournal of mammalian evolution · 2021Article
- Article
- Comparative skeletal anatomy of neonatal ursids and the extreme altriciality of the giant panda.Journal of anatomy · 2020Article
- It takes two: Building the vertebrate skull from chondrocranium and dermatocranium.Vertebrate zoology · 2020Article
- Resolving homology in the face of shifting germ layer origins: Lessons from a major skull vault boundary.eLife · 2019Review
- Cetacean Skull Telescoping Brings Evolution of Cranial Sutures into Focus.Anatomical record (Hoboken, N.J. : 2007) · 2019Review
- Unexpected evolutionary patterns of dental ontogenetic traits in cetartiodactyl mammals.Proceedings. Biological sciences · 2019Article
- A 3D view of early mammals.Nature · 2018Article
- Creating diversity in mammalian facial morphology: a review of potential developmental mechanisms.EvoDevo · 2018Review
- Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017Article
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Authors and funding
3 authors at 3 institutions in 3 countries.
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Abstract
The homologies of mammalian skull elements are now fairly well established, except for the controversial interparietal bone. A previous experimental study reported an intriguing mixed origin of the interparietal: the medial portion being derived from the neural crest cells, whereas the lateral portion from the mesoderm. The evolutionary history of such mixed origin remains unresolved, and contradictory reports on the presence or absence and developmental patterns of the interparietal among mammals have complicated the question of its homology. Here we provide an alternative perspective on the evolutionary identity of the interparietal, based on a comprehensive study across more than 300 extinct and extant taxa, integrating embryological and paleontological data. Although the interparietal has been regarded as being lost in various lineages, our investigation on embryos demonstrates its presence in all extant mammalian "orders." The generally accepted paradigm has regarded the interparietal as consisting of two elements that are homologized to the postparietals of basal amniotes. The tabular bones have been postulated as being lost during the rise of modern mammals. However, our results demonstrate that the interparietal consists not of two but of four elements. We propose that the tabulars of basal amniotes are conserved as the lateral interparietal elements, which quickly fuse to the medial elements at the embryonic stage, and that the postparietals are homologous to the medial elements. Hence, the dual developmental origin of the mammalian interparietal can be explained as the evolutionary consequence of the fusion between the crest-derived "postparietals" and the mesoderm-derived "tabulars."
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