Evidence map›Paper›PMID 22891224›Full record

ArticlePediatrics2012

Persistent snoring in preschool children: predictors and behavioral and developmental correlates.

Dean W Beebe, Joseph Rausch, Kelly C Byars, Bruce Lanphear, Kimberly Yolton

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00129324 (Neurobehavioral Effects of Prevalent Neurotoxicants in Children), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00129324 nacompletednot on this map

Neurobehavioral Effects of Prevalent Neurotoxicants in Children: A Cohort Study of the Cincinnati Center for Children's Environmental Health

TypeinterventionalSponsorNational Institute of Environmental Health Sciences (NIEHS)Ran2003 to 2018Enrolled468ConditionsEnvironmental Exposures, Child Development, Lead and Injury ReductionArmsLead Hazard Control Intervention, Injury Hazard Control Intervention
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Review
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  14. Risk factors of obstructive sleep apnea syndrome in children.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2020
    Article
  15. Risk Factors for Obstructive Sleep Apnea Syndrome in Children: State of the Art.International journal of environmental research and public health · 2019
    Review
  16. Article
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  20. Mandibular movements identify respiratory effort in pediatric obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Dean W BeebeDivision of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, MLC 3015, 3333 Burnet Ave, Cincinnati, OH 45229-3039, USA. dean.beebe@cchmc.org
Joseph Rausch
Kelly C Byars
Bruce Lanphear
Kimberly Yolton
University of Cincinnati Medical Center · USBritish Columbia Children's Hospital · CACincinnati Children's Hospital Medical Center · US

Funding

Study of Prevalent Neurotoxicants in ChildrenP01ES011261 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI LANPHEAR, BRUCE P · 2001 to 2006
$6.4M
Neurobehavioral Effects of Insecticide Exposure in Pregnancy and Early ChildhoodR01ES015517 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI YOLTON, KIMBERLY · 2009 to 2010
$1.5M
NIEHS NIH HHS P01 ES011261NIEHS NIH HHS P01 ES11261NIEHS NIH HHS R01 ES015517NIEHS NIH HHS R01 ES015517-01A1
6 · The paper itself

Abstract

objectiveTo clarify whether persistent snoring in 2- to 3-year-olds is associated with behavioral and cognitive development, and to identify predictors of transient and persistent snoring.

methodsTwo hundred forty-nine mother/child pairs participated in a prospective birth cohort study. Based upon parental report of loud snoring ≥ 2 times weekly at 2 and 3 years of age, children were designated as nonsnorers, transient snorers (snored at 2 or 3 years of age, but not both), or persistent snorers (snored at both ages). We compared groups by using validated measures of behavioral and cognitive functioning. Potential predictors of snoring included child race and gender, socioeconomic status (parent education and income), birth weight, prenatal tobacco exposure (maternal serum cotinine), childhood tobacco exposure (serum cotinine), history and duration of breast milk feeding, and body mass relative to norms.

resultsIn multivariable analyses, persistent snorers had significantly higher reported overall behavior problems, particularly hyperactivity, depression, and inattention. Nonsnorers had significantly stronger cognitive development than transient and persistent snorers in unadjusted analyses, but not after demographic adjustment. The strongest predictors of the presence and persistence of snoring were lower socioeconomic status and the absence or shorter duration of breast milk feeding. Secondary analyses suggested that race may modify the association of childhood tobacco smoke exposure and snoring.

conclusionsPersistent, loud snoring was associated with higher rates of problem behaviors. These results support routine screening and tracking of snoring, especially in children from low socioeconomic backgrounds; referral for follow-up care of persistent snoring in young children; and encouragement and facilitation of infant breastfeeding.

Indexed as

Child DevelopmentBreast FeedingChild Behavior DisordersChild, PreschoolCognitionCohort StudiesFemaleHumansMalePregnancyPrenatal Exposure Delayed EffectsRisk-TakingSnoringSocioeconomic Factors

Identifiers

PMID22891224
PMCPMC3428758
OpenAlexW2136910986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.