Trial reportCanadian respiratory journal
Oscillometric and spirometric bronchodilator response in preschool children with and without asthma.
Trial report in Canadian respiratory journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Small airway bronchodilator response to different doses of salbutamol in 7-year-old children.Respiratory research · 2017Trial
- Diagnostic accuracy of the bronchodilator response in children.The Journal of allergy and clinical immunology · 2013Trial
- Bronchodilator response assessment through impulse oscillometry system and spirometry in children and adolescents with cystic fibrosis.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024Article
- Lung mechanics and respiratory morbidities in school-age children born moderate-to-late preterm.Pediatric research · 2022Article
- Sex differences in body composition affect total airway resistance during puberty.BMC pediatrics · 2022Article
- Small Airway Dysfunction Measured by Impulse Oscillometry and Fractional Exhaled Nitric Oxide Is Associated With Asthma Control in Children.Frontiers in pediatrics · 2022Article
- Usefulness of impulse oscillometry for the assessment of bronchodilator response in elderly patients with chronic obstructive airway disease.Journal of thoracic disease · 2019Article
- Question 3: Can we diagnose asthma in children under the age of 5 years?Paediatric respiratory reviews · 2019Review
- Impulse oscillometry reference values and bronchodilator response in three- to five-year old children living at high altitude.Journal of asthma and allergy · 2019Article
- Lung function tests to monitor respiratory disease in preschool children.Acta bio-medica : Atenei Parmensis · 2018Review
- Input oscillometry and the forced oscillation technique for assessing lung function in preschool children with asthma.Pediatric investigation · 2018Review
- The case for impulse oscillometry in the management of asthma in children and adults.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBronchodilator responses (BDR) are routinely used in the diagnosis and management of asthma; however, their acceptability and repeatability have not been evaluated using quality control criteria for preschool children.
objectivesTo compare conventional spirometry with an impulse oscillometry system (IOS) in healthy and asthmatic preschool children.
methodsData from 30 asthmatic children and 29 controls (two to six years of age) who underwent IOS and spirometry before and after salbutamol administration were analyzed.
resultsStable asthmatic subjects significantly differed versus controls in their spirometry-assessed BDR (forced expiratory volume in 1 s [FEV1], forced vital capacity and forced expiratory flow at 25% to 75% of forced vital capacity) as well as their IOS-assessed BDR (respiratory resistance at 5 Hz [Rrs5], respiratory reactance at 5 Hz and area under the reactance curve). However, comparisons based on the area under the ROC curve for ΔFEV1 %initial versus ΔRrs5 % initial were 0.82 (95% CI 0.71 to 0.93) and 0.75 (95% CI 0.62 to 0.87), respectively. Moreover, the sensitivity and specificity for ΔFEV1 >=9% were 0.53 and 0.93, respectively. Importantly, sensitivity increased to 0.63 when either ΔFEV1 >=9% or ΔRrs5 >=29% was considered as an additional criterion for the diagnosis of asthma.
conclusionThe accuracy of asthma diagnosis in preschool children may be increased by combining spirometry with IOS when measuring BDR.
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