Evidence map›Paper›PMID 22891106›Full record

ReviewMethodist DeBakey cardiovascular journal2012

High-resolution CT vascular imaging using blood pool contrast agents.

Ananth V Annapragada, Eric Hoffman, Abhay Divekar, Efstathios Karathanasis, Ketan B Ghaghada

Open access · diamondAbstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Advances in micro-CT imaging of small animals.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Cerebral vascular leak in a mouse model of amyloid neuropathology.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2014
    Article
  14. Photon-counting Detector CT: System Design and Clinical Applications of an Emerging Technology.Radiographics : a review publication of the Radiological Society of North America, Inc
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ananth V AnnapragadaSingleton Department of Pediatric Radiology, Texas Children’s Hospital, Houston, TX, USA.
Eric Hoffman
Abhay Divekar
Efstathios Karathanasis
Ketan B Ghaghada
University of Iowa · USBoston Children's Hospital · USCase Western Reserve University · USTexas Children's Hospital · US

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Drew James Adams · 1987 to 2026
$142.3M
NCTX, a novel liposomal CT contrast agent for blood pool imagingR44EB004700 · NIBIB · MARVAL BIOSCIENCES, INC. · PI LEBOVITZ, RUSSELL M · 2007 to 2008
$685k
NCI NIH HHS P30 CA043703NIBIB NIH HHS 2R44EB04700
6 · The paper itself

Abstract

While the evolution of computed tomography imaging in the last 2 decades has been driven almost exclusively by improvements in the instrumentation and processing algorithms, there have been comparatively modest advances in contrast agent technology.A notable change in the last decade has been the development of blood pool contrast agents based on nanoparticle technology.While not yet ready for clinical use, the stable and uniform opacification provided by these agents in normal vasculature and controlled extravasation in compromised vasculature enables novel techniques for imaging and diagnosis of pathologies. This manuscript presents preclinical examples demonstrating cardiovascular pathologies and tumor characterization by high-resolution computed tomography imaging.

Indexed as

Contrast MediaNanomedicineNanoparticlesTomography, X-Ray ComputedAnimalsCardiologyCardiovascular DiseasesHumansPredictive Value of TestsWhole Body ImagingContrast Mediablood poolcomputed tomographycontrast agentCTliposometumor

Identifiers

PMID22891106
PMCPMC3405778
OpenAlexW2044617758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.