ReviewNature reviews. Microbiology2012
Genomic sequencing of uncultured microorganisms from single cells.
Review in Nature reviews. Microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
113 citing papers in PubMed.
- Functional Metagenomics Reveals Gut Microbial Biosynthetic Potential for Essential Nutrients in Juvenile Chum Salmon.Environmental microbiology · 2026Article
- Ensemble test for microbiome data.Microbiome · 2026Article
- Mining Microbial Dark Matter: Advanced Cultivation Techniques for Bioactive Compound Discovery.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Exploring Microbial Dark Matter for the Discovery of Novel Natural Products: Characteristics, Abundance Challenges and Methods.Journal of microbiology and biotechnology · 2024Review
- Advances in single-cell sequencing technology in microbiome research.Genes & diseases · 2024Review
- Article
- Raman cell sorting for single-cell research.Frontiers in bioengineering and biotechnology · 2024Review
- MKMR: a multi-kernel machine regression model to predict health outcomes using human microbiome data.Briefings in bioinformatics · 2023Article
- Chimera: The spoiler in multiple displacement amplification.Computational and structural biotechnology journal · 2023Review
- Biological functions of endophytic bacteria inFrontiers in microbiology · 2023Article
- Batch effects removal for microbiome data via conditional quantile regression.Nature communications · 2022Article
- De novo assembly of human genome at single-cell levels.Nucleic acids research · 2022Article
- Dissecting the dominant hot spring microbial populations based on community-wide sampling at single-cell genomic resolution.The ISME journal · 2022Article
- An Adaptive and Robust Test for Microbial Community Analysis.Frontiers in genetics · 2022Article
- Prokaryotic and eukaryotic diversity in hydrothermal continental systems.Archives of microbiology · 2021Review
- Applications of Single-Cell DNA Sequencing.Annual review of genomics and human genetics · 2021Review
- Casting Light on the Adaptation Mechanisms and Evolutionary History of the Widespread Sumerlaeota.mBio · 2021Article
- Ecogenomics of the SAR11 clade.Environmental microbiology · 2020Article
- Identification of Microbial Profiles in Heavy-Metal-Contaminated Soil from Full-Length 16S rRNA Reads Sequenced by a PacBio System.Microorganisms · 2019Article
- Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi.Applied microbiology and biotechnology · 2019Review
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sequencing DNA from single cells has opened new windows onto the microbial world. It is becoming routine to sequence bacterial species directly from environmental samples or clinical specimens without the need to develop cultivation methods. Recent technical improvements often allow nearly complete genome assembly from these otherwise inaccessible species. New bioinformatics methods are also improving genome assembly from single cells. The use of single-cell sequencing in combination with metagenomic analysis is also emerging as a powerful new strategy to analyse bacterial communities. Here, the technical developments that have enabled single-cell sequencing, as well as some of the most exciting applications of this approach from the past few years, are reviewed.
Indexed as
Identifiers
22890147What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.