Evidence map›Paper›PMID 22889039›Full record

ArticleExperimental and clinical psychopharmacology2012

Cue reactivity as a predictor of successful abstinence initiation among adult smokers.

Cynthia A Conklin, Craig S Parzynski, Ronald P Salkeld, Kenneth A Perkins, Carolyn A Fonte

Abstract read
In one paragraph

Article in Experimental and clinical psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Mechanisms of change in a randomized control pilot study of partner-involved financial incentive treatments for dual-smoking couples.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Trial
  2. Partner-Involved Financial Incentives for Smoking Cessation in Dual-Smoker Couples: A Randomized Pilot Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Trial
  3. Augmented reality for extinction of cue-provoked urges to smoke: Proof of concept.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022
    Trial
  4. Initial Evaluation of Fenofibrate for Efficacy in Aiding Smoking Abstinence.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Trial
  5. Article
  6. Testing Augmented Reality for Eliciting Cue-Provoked Urges to Smoke: Toward Moving Cue-Exposure Into the Real World.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Article
  7. The clinical potential of augmented reality.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2020
    Article
  8. Article
  9. Combined Smoking Cues Enhance Reactivity and Predict Immediate Subsequent Smoking.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Examining the relationship between cue-induced craving and actual smoking.Experimental and clinical psychopharmacology · 2015
    Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cynthia A ConklinWestern Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. conklinca@upmc.edu
Craig S Parzynski
Ronald P Salkeld
Kenneth A Perkins
Carolyn A Fonte

Funding

TRANSDISCIPLINARY TOBACCO USE RESEARCH CENTERSP50CA084718 · NCI · UNIVERSITY OF PENNSYLVANIA · PI LERMAN, CARYN · 1999 to 2008
$17.8M
Neuroimaging Abstinence and Medication ResponseP50CA143187 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BALDWIN, DONALD A · 2009 to 2013
$8.6M
Self-report and behavioral reactivity to combined smoking cuesR01DA023646 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONKLIN, CYNTHIA A. · 2008 to 2012
$1.3M
NCI NIH HHS CA143187NCI NIH HHS P50 CA143187NIDA NIH HHS DA023646NIDA NIH HHS R01 DA023646
6 · The paper itself

Abstract

The association between smokers' cue-induced craving and subsequent ability to initiate abstinence is unclear. Dependent smokers (N = 158) completed a single cue-reactivity session prior to participating in a larger within-subjects study, which independently examined predictors of initiating quitting during 5 days each on nicotine versus placebo patch. In the larger study, all smokers used nicotine and placebo patch (double blind) for 1 week each following a preceding week of ad lib smoking, in a 2 × 2 cross-over design. Generalized estimating equation (GEE) models determined the predictive ability of cue-induced craving (cue reactivity) on subsequent success at initiating a quit attempt (at least 24 hr quit) for each patch condition. Smokers who exhibited greater craving during exposure to smoking cues had significantly greater odds of successfully initiating abstinence during either quit attempt week (i.e., the nicotine or placebo patch week). This relationship was not statistically significant for self-reported craving in response to neutral cues. However, a greater smoking-neutral cue difference score for cue-induced craving was also a significant predictor of successfully initiating abstinence, but only among those not monetarily reinforced. Implications of these seemingly counterintuitive findings are discussed.

Indexed as

MotivationAdolescentAdultDouble-Blind MethodFemaleHumansMaleMiddle AgedModels, PsychologicalNicotinePlacebosSmoking CessationYoung AdultNicotinePlacebos

Identifiers

PMID22889039
PMCPMC3752834

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.