ArticleInternational journal of nanomedicine2012
Stability of membranous nanostructures: a possible key mechanism in cancer progression.
Article in International journal of nanomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 45 citations in OpenAlex.
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- On the Role of Curved Membrane Nanodomains, and Passive and Active Skeleton Forces in the Determination of Cell Shape and Membrane Budding.International journal of molecular sciences · 2021Article
- Minimizing isotropic and deviatoric membrane energy - An unifying formation mechanism of different cellular membrane nanovesicle types.PloS one · 2020Article
- Inception Mechanisms of Tunneling Nanotubes.Cells · 2019Review
- On the role of external force of actin filaments in the formation of tubular protrusions of closed membrane shapes with anisotropic membrane components.European biophysics journal : EBJ · 2017Article
- Programmed Fetal Membrane Senescence and Exosome-Mediated Signaling: A Mechanism Associated With Timing of Human Parturition.Frontiers in endocrinology · 2017Review
- Biological properties of extracellular vesicles and their physiological functions.Journal of extracellular vesicles · 2015Article
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- The role of extracellular vesicles in phenotypic cancer transformation.Radiology and oncology · 2013Review
- Interaction between dipolar lipid headgroups and charged nanoparticles mediated by water dipoles and ions.International journal of molecular sciences · 2013Article
- Monovalent ions and water dipoles in contact with dipolar zwitterionic lipid headgroups-theory and MD simulations.International journal of molecular sciences · 2013Article
- Morphological alterations of T24 cells on flat and nanotubular TiO2 surfaces.Croatian medical journal · 2012Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Membranous nanostructures, such as nanovesicles and nanotubules, are an important pool of biological membranes. Recent results indicate that they constitute cell-cell communication systems and that cancer development is influenced by these systems. Nanovesicles that are pinched off from cancer cells can move within the circulation and interact with distant cells. It has been suggested and indicated by experimental evidence that nanovesicles can induce metastases from the primary tumor in this way. Therefore, it is of importance to understand better the mechanisms of membrane budding and vesiculation. Here, a theoretical description is presented concerning consistently related lateral membrane composition, orientational ordering of membrane constituents, and a stable shape of nanovesicles and nanotubules. It is shown that the character of stable nanostructures reflects the composition of the membrane and the intrinsic shape of its constituents. An extension of the fluid mosaic model of biological membranes is suggested by taking into account curvature-mediated orientational ordering of the membrane constituents on strongly anisotropically curved regions. Based on experimental data for artificial membranes, a possible antimetastatic effect of plasma constituents via mediation of attractive interaction between membranous structures is suggested. This mediated attractive interaction hypothetically suppresses nanovesiculation by causing adhesion of buds to the mother membrane and preventing them from being pinched off from the membrane.
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