Evidence map›Paper›PMID 22887823›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Labeling of neuronal receptors and transporters with quantum dots.

Jerry C Chang, Oleg Kovtun, Randy D Blakely, Sandra J Rosenthal

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Optical bio/chemical sensors for vitamin BBeilstein journal of nanotechnology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jerry C ChangDepartment of Chemistry, Vanderbilt University, Nashville, TN, USA.
Oleg Kovtun
Randy D Blakely
Sandra J Rosenthal

Funding

Regulation of Serotonin TransportersR01MH094527 · NIMH · VANDERBILT UNIVERSITY · PI BLAKELY, RANDY D. · 2011 to 2021
$4.4M
Probes:Quantitative Optical and Electron Microscopy(RMI)P20GM072048 · NIGMS · VANDERBILT UNIVERSITY · PI PISTON, DAVID W. · 2004 to 2007
$2.7M
Quantum Dot Nanoconjugate Imaging of Neural ReceptorsR01EB003728 · NIBIB · VANDERBILT UNIVERSITY · PI ROSENTHAL, SANDRA JEAN · 2004 to 2010
$2.1M
NIBIB NIH HHS EB003728NIBIB NIH HHS R01 EB003728NIGMS NIH HHS GM72048NIGMS NIH HHS P20 GM072048NIMH NIH HHS MH07802NIMH NIH HHS MH094527NIMH NIH HHS R01 MH094527
6 · The paper itself

Abstract

The ability to efficiently visualize protein targets in cells is a fundamental goal in biological research. Recently, quantum dots (QDots) have emerged as a powerful class of fluorescent probes for labeling membrane proteins in living cells because of breakthrough advances in QDot surface chemistry and biofunctionalization strategies. This review discusses the increasing use of QDots for fluorescence imaging of neuronal receptors and transporters. The readers are briefly introduced to QDot structure, photophysical properties, and common synthetic routes toward the generation of water-soluble QDots. The following section highlights several reports of QDot application that seek to unravel molecular aspects of neuronal receptor and transporter regulation and trafficking. This article is closed with a prospectus of the future of derivatized QDots in neurobiological and pharmacological research.

Indexed as

Quantum DotsAnimalsFluorescent DyesHumansMolecular ImagingMolecular ProbesNeuronsNeurotransmitter Transport ProteinsProtein TransportReceptors, NeurotransmitterFluorescent DyesMolecular ProbesNeurotransmitter Transport ProteinsReceptors, Neurotransmitter

Identifiers

PMID22887823
PMCPMC3753009

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.