Trial reportEuropean radiology2013
Magnetic resonance imaging to assess the effect of exercise training on pulmonary perfusion and blood flow in patients with pulmonary hypertension.
Trial report in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 6 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Pulmonary hypertension and the role of MRI flow assessment: a systematic review.The British journal of radiology · 2025Pooled it
- Effectiveness and safety of home-basedEuropean respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Exercise-based rehabilitation programmes for pulmonary hypertension.The Cochrane database of systematic reviews · 2023Pooled it
- Walking for hypertension.The Cochrane database of systematic reviews · 2021Pooled it
- Exercise-based rehabilitation programmes for pulmonary hypertension.The Cochrane database of systematic reviews · 2017Pooled it
- Exercise training improves physical fitness in patients with pulmonary arterial hypertension: a systematic review and meta-analysis of controlled trials.BMC pulmonary medicine · 2015Pooled it
- Long-Term Effect of an Exercise Training Program on Physical Functioning and Quality of Life in Pulmonary Hypertension: A Randomized Controlled Trial.BioMed research international · 2021Trial
- Trial
- Non-invasive determination of pulmonary hypertension with dynamic contrast-enhanced computed tomography: a pilot study.European radiology · 2014Trial
- Physical exercise for pulmonary arterial hypertension diagnosis and therapy.International journal of cardiology. Congenital heart disease · 2025Review
- Rehabilitation applications and progress in managing pulmonary hypertension.Frontiers in medicine · 2025Review
- 2023 TSOC-TACVPR-TACPAH Consensus Statement of the Rehabilitation on Patients with Pulmonary Hypertension.Acta Cardiologica Sinica · 2024Article
- Barriers to and facilitators of physical activity in pediatric pulmonary hypertension.Pulmonary circulation · 2024Article
- Creating a digital approach for promoting physical activity in pediatric pulmonary hypertension: A framework for future interventions.Pulmonary circulation · 2024Article
- Effects of combined aerobic, resistance and inspiratory training in patients with pulmonary hypertension: A systematic review.World journal of critical care medicine · 2024Article
- Role of pulmonary perfusion magnetic resonance imaging for the diagnosis of pulmonary hypertension: A review.World journal of radiology · 2023Review
- Exercised-based cardiac rehabilitation associates with lower all-cause mortality in patients with primary pulmonary hypertension.Frontiers in sports and active living · 2023Article
- Pulmonary Arteriovenous Pressure Gradient and Time-Averaged Mean Velocity of Small Pulmonary Arteries Can Serve as Sensitive Biomarkers in the Diagnosis of Pulmonary Arterial Hypertension: A Preclinical Study by 4D-Flow MRI.Diagnostics (Basel, Switzerland) · 2021Article
- Cardiac Rehabilitation in German Speaking Countries of Europe-Evidence-Based Guidelines from Germany, Austria and Switzerland LLKardReha-DACH-Part 1.Journal of clinical medicine · 2021Review
- High Right Ventricular Afterload during Exercise in Patients with Pulmonary Arterial Hypertension.Journal of clinical medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate whether careful exercise training improves pulmonary perfusion and blood flow in patients with pulmonary hypertension (PH), as assessed by magnetic resonance imaging (MR).
methodsTwenty patients with pulmonary arterial hypertension or inoperable chronic thromboembolic PH on stable medication were randomly assigned to control (n = 10) or training groups (n = 10). Training group patients received in-hospital exercise training; patients of the sedentary control group received conventional rehabilitation. Medication remained unchanged during the study period. Changes of 6-min walking distance (6MWD), MR pulmonary flow (peak velocity) and MR perfusion (pulmonary blood volume) were assessed from baseline to week 3.
resultsAfter 3 weeks of training, increases in mean 6MWD (P = 0.004) and mean MR flow peak velocity (P = 0.012) were significantly greater in the training group. Training group patients had significantly improved 6MWD (P = 0.008), MR flow (peak velocity -9.7 ± 8.6 cm/s, P = 0.007) and MR perfusion (pulmonary blood volume +2.2 ± 2.7 mL/100 mL, P = 0.017), whereas the control group showed no significant changes.
conclusionThe study indicates that respiratory and physical exercise may improve pulmonary perfusion in patients with PH. Measurement of MR parameters of pulmonary perfusion might be an interesting new method to assess therapy effects in PH. The results of this initial study should be confirmed in a larger study group.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.