Evidence map›Paper›PMID 22886321›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2012

Prevalence and predictors of abnormal bone mineral metabolism in recently diagnosed adult celiac patients.

Sudheer D Chakravarthi, Kapil Jain, Rakesh Kochhar, Sanjay K Bhadada, Niranjan Khandelwal, Anil Bhansali, Usha Dutta, Chander K Nain, Kartar Singh

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

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5citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  4. Static and time-dependent mechanical response of organic matrix of bone.Journal of the mechanical behavior of biomedical materials · 2019
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5 · Who and what money

Authors and funding

9 authors.

Sudheer D ChakravarthiDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India.
Kapil Jain
Rakesh Kochhar
Sanjay K Bhadada
Niranjan Khandelwal
Anil Bhansali
Usha Dutta
Chander K Nain
Kartar Singh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThis study aimed to evaluate the prevalence of low bone mineral density (BMD) in recently diagnosed adult celiac patients and to identify the factors associated with this.

methodsWe investigated 54 newly diagnosed adult celiac patients between February 2008 and April 2009. BMD was measured in all patients and its correlation with clinical and biochemical parameters was analyzed.

resultsFifty-four (24 male) newly diagnosed celiac patients with a mean±SD age of 30.6 ± 9.3 years (range 18-50) were included. Thirty-nine (72.2 %) presented with intestinal symptoms, and the rest with extraintestinal symptoms. Low vitamin D levels were seen in 11 (20.3 %) patients and elevated iPTH (secondary hyperparathyroidism) in 12 (22.2 %) patients. Twenty-one (39 %) patients had normal BMD, 23 (43 %) had osteopenia (T-score -1 to -2.5), and 10 (18 %) patients had osteoporosis (T-score <-2.5). A statistically significant association was seen between BMD and age of onset, duration of illness, serum tTGA levels, serum vitamin D levels, and histopathological changes.

conclusionsLow BMD is common in newly diagnosed adult celiac patients with approximately one fifth of them having osteoporosis. BMD should be measured in all newly diagnosed celiac patients and calcium and vitamin D supplementation included in the treatment regimen.

Indexed as

Bone DensityAbsorptiometry, PhotonAdolescentAdultBone and BonesCeliac DiseaseFemaleHumansHyperparathyroidism, SecondaryMaleMiddle AgedOsteoporosisParathyroid HormonePrevalenceVitamin DVitamin D DeficiencyParathyroid HormoneVitamin D

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.