Evidence map›Paper›PMID 22886106›Full record

ArticleArchives of osteoporosis2011

Risk factors for fractures among Japanese-American men: The Honolulu Heart Program and Honolulu-Asia Aging Study.

Claudia C Ma, Cecil M Burchfiel, John Grove, Desta Fekedulegn, Yuanan Lu, Michael E Andrew, Bradley Willcox, Kamal H Masaki, J David Curb, Beatriz L Rodriguez

Abstract read
In one paragraph

Article in Archives of osteoporosis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. The association of coffee consumption with the risk of osteoporosis and fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
  2. Pooled it
  3. Socio-economic inequalities in fragility fracture incidence: a systematic review and meta-analysis of 61 observational studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Pooled it
  4. Pooled it
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Claudia C MaBiostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505-2888, USA. iia4@cdc.gov
Cecil M Burchfiel
John Grove
Desta Fekedulegn
Yuanan Lu
Michael E Andrew
Bradley Willcox
Kamal H Masaki
J David Curb
Beatriz L Rodriguez

Funding

Epidemiology of Brain Aging in the Very OldU01AG019349 · NIA · KUAKINI MEDICAL CENTER · PI WHITE, LON RAY · 2001 to 2011
$14.0M
EPIDEMIOLOGY OF AGING AND DEMENTIA - AUTOPSY RESEARCHR01AG017155 · NIA · KUAKINI MEDICAL CENTER · PI WHITE, LON RAY · 2000 to 2007
$6.7M
HONOLULU HEART PROGRAMN01HC005102 · HC · KUAKINI MEDICAL CENTER · PI CURB, JESS DAVID · 1990 to 1997
–
Intramural NIH HHSNHLBI NIH HHS N01 HC005102NHLBI NIH HHS N01 HC05102NIA NIH HHS R01 AG0-17155 S1NIA NIH HHS U01 AG019349
6 · The paper itself

Abstract

unlabelledBaseline risk factors were associated with fractures that developed after 29-31 years among Japanese-American men. Hip fracture risk increased with increasing BMI (28% increase for 1 U increase), physical activity (7% increase for 1 U increase), and was decreased with increasing arm girth (27% decrease for 1 U increase). PURPOSE: The objective of this study was to identify risk factors among Japanese-American men aged 45-68 years at baseline that were associated with prevalence and incidence of fractures at advanced age.

methodsWe used baseline information from Honolulu Heart Program (HHP) and Honolulu-Asia Aging Study (HAAS). The HHP was a prospective study with primary focus on risk factors for cardiovascular disease. A cohort of 8,006 men of Japanese ancestry aged 45-68 years residing on Oahu was recruited in 1965 and followed for 31 years. The HAAS started in 1991 in conjunction with the HHP with a focus on age-related health conditions. Self-reported hip, spine, and forearm fracture prevalence was ascertained in 1991-1993 among 3,845 men aged 71-93 years. Incidence was obtained during the period (1994-1999) among 2,737 men aged 74-98 years. Poisson regression models were used to determine multi-variable adjusted prevalence and incidence ratios for fracture.

resultsIncident hip fracture was directly associated with baseline body mass index (BMI) and physical activity, and inversely associated with left upper arm girth. Incident spine fracture was directly associated with baseline age. Prevalent hip fracture was directly associated with baseline pack-years of smoking. Prevalent spine fracture was inversely associated with baseline education, and directly associated with standing height and use of medication for diabetes. Prevalent forearm fracture was inversely associated with baseline age, and directly associated with education.

conclusionsResults indicated that multiple baseline demographic lifestyle and anthropometric characteristics predict fracture risk at advanced age. In addition, associations varied by fracture location.

Indexed as

AgedAged, 80 and overAsianFractures, BoneHawaiiHumansIncidenceJapanMaleMiddle AgedPrevalenceRisk Factors

Identifiers

PMID22886106
PMCPMC3565433

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.