Evidence map›Paper›PMID 22886069›Full record

ArticleGlycoconjugate journal2013

Targeting the glycoproteome.

Jonas Nilsson, Adnan Halim, Ammi Grahn, Göran Larson

Abstract read
In one paragraph

Article in Glycoconjugate journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. The Hitchhiker's guide to glycoproteomics.Biochemical Society transactions · 2021
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. The O-GlcNAc Modification on Kinases.ACS chemical biology · 2020
    Article
  9. Review
  10. Glycans in drug discovery.MedChemComm · 2019
    Review
  11. Review
  12. Chemical Glycoproteomics.Chemical reviews · 2016
    Review
  13. Glycoproteins and glycoproteomics in pancreatic cancer.World journal of gastroenterology · 2016
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Genetic glycoengineering in mammalian cells.The Journal of biological chemistry
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonas NilssonDepartment of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Gothenburg 413 45, Sweden.
Adnan Halim
Ammi Grahn
Göran Larson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite numerous original publications describing the structural complexity of N- and O-linked glycans on glycoproteins, only very few answer the basic question of which particular glycans are linked to which amino acid residues along the polypeptide chain. Such structural information is of fundamental importance for understanding the biological roles of complex glycosylations as well as deciphering their non-template driven biosynthesis. This review focuses on presenting and commenting on recent strategies, specifically aimed at identifying the glycoproteome of cultured cells and biological samples, using targeted and global enrichment procedures and utilizing the high resolution power, high through-put capacity and complementary fragmentation techniques of tandem mass spectrometry. The goal is to give an update of this emerging field of protein and glyco-sciences and suggest routes to bridge the data gap between the two aspects of glycoprotein characteristics, i.e. glycan structures and their attachment sites.

Indexed as

ProteomeCells, CulturedChromatography, LiquidGlycopeptidesGlycoproteinsGlycosylationHumansHydrophobic and Hydrophilic InteractionsMass SpectrometryModels, BiologicalGlycopeptidesGlycoproteinsProteome

Identifiers

PMID22886069
PMCPMC3552370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.