ArticleJournal of laboratory automation2012
A serial sample loading system: interfacing multiwell plates with microfluidic devices.
Article in Journal of laboratory automation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Automated and miniaturized screening of antibiotic combinationsActa pharmaceutica Sinica. B · 2024Article
- Assessment of UTI Diagnostic Techniques Using the Fuzzy-PROMETHEE Model.Diagnostics (Basel, Switzerland) · 2023Article
- Emerging platforms for high-throughput enzymatic bioassays.Trends in biotechnology · 2023Review
- Rapid parallel generation of a fluorescently barcoded drop library from a microtiter plate using the plate-interfacing parallel encapsulation (PIPE) chip.Lab on a chip · 2022Article
- Facile and scalable tubing-free sample loading for droplet microfluidics.Scientific reports · 2022Article
- 96-Well Oxygen Control Using a 3D-Printed Device.Analytical chemistry · 2021Article
- micrIO: an open-source autosampler and fraction collector for automated microfluidic input-output.Lab on a chip · 2020Article
- Pressure-Driven Micro-Casting for Electrode Fabrication and Its Applications in Wear Grain Detections.Materials (Basel, Switzerland) · 2019Article
- Versatile Analysis of DNA-Biomolecule Interactions in Solution by Hydrodynamic Separation and Single Molecule Detection.Analytical chemistry · 2019Article
- Droplet microfluidics for high-sensitivity and high-throughput detection and screening of disease biomarkers.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2018Review
- Automated fluid delivery from multiwell plates to microfluidic devices for high-throughput experiments and microscopy.Scientific reports · 2018Article
- Accelerating bacterial growth detection and antimicrobial susceptibility assessment in integrated picoliter droplet platform.Biosensors & bioelectronics · 2017Article
- New and developing diagnostic technologies for urinary tract infections.Nature reviews. Urology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
There is an increasing demand for novel high-throughput screening (HTS) technologies in the pharmaceutical and biotechnological industries. The robotic sample-handling techniques currently used in these industries, although fast, are still limited to operating in multiwell plates with the sample volumes per reaction in the microliter regime. Digital microfluidics offers an alternative for reduction in sample volume consumption for HTS but lacks a reliable technique for transporting a large number of samples to the microfluidic device. In this report, we develop a technique for serial delivery of sample arrays to a microfluidic device from multiwell plates, through a single sample inlet. Under this approach, a serial array of sample plugs, separated by an immiscible carrier fluid, is loaded into a capillary and delivered to a microfluidic device. Similar approaches have been attempted in the past, however, either with a slower sample loading device such as a syringe pump or vacuum-based sample loading with limited driving pressure. We demonstrated the application of our positive-pressure-based serial sample loading (SSL) system to load a series of sample plugs into a capillary. The adaptability of the SSL system to generate sample plugs with a variety of volumes in a predictable manner was also demonstrated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.