ArticleIntensive care medicine2012
Zero tolerance prescribing: a strategy to reduce prescribing errors on the paediatric intensive care unit.
Article in Intensive care medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Interventions to Reduce Pediatric Prescribing Errors in Professional Healthcare Settings: A Systematic Review of the Last Decade.Paediatric drugs · 2021Pooled it
- Mapping the prevalence and nature of drug related problems among hospitalised children in the United Kingdom: a systematic review.BMC pediatrics · 2019Pooled it
- Prevalence and Nature of Medication Errors and Preventable Adverse Drug Events in Paediatric and Neonatal Intensive Care Settings: A Systematic Review.Drug safety · 2019Pooled it
- Prevalence of Medication Errors Among Paediatric Inpatients: Systematic Review and Meta-Analysis.Drug safety · 2019Pooled it
- Global Prevalence and Associated Factors of Medication Errors in Hospitalized Pediatric Patients: Systematic Review and Meta-Analysis.JMIR pediatrics and parenting · 2026Review
- Interventions to reduce medication errors in neonatal care: a systematic review.Therapeutic advances in drug safety · 2018Review
- Occurrence of Potential Adverse Drug Events from Prescribing Errors in a Pediatric Intensive and High Dependency Unit in Hong Kong: An Observational Study.Paediatric drugs · 2017Observational
- Paediatric Patient Safety and the Need for Aviation Black Box Thinking to Learn From and Prevent Medication Errors.Paediatric drugs · 2017Review
- Drug Utilization on Neonatal Wards: A Systematic Review of Observational Studies.Frontiers in pharmacology · 2017Article
- Patient Safety Incidents Involving Sick Children in Primary Care in England and Wales: A Mixed Methods Analysis.PLoS medicine · 2017Article
- Impact of computerized physician order entry (CPOE) on PICU prescribing errors.Intensive care medicine · 2014Article
- Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient-ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea.Intensive care medicine · 2013Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo establish the baseline prescribing error rate in a tertiary paediatric intensive care unit (PICU) and to determine the impact of a zero tolerance prescribing (ZTP) policy incorporating a dedicated prescribing area and daily feedback of prescribing errors.
methodsA prospective, non-blinded, observational study was undertaken in a 12-bed tertiary PICU over a period of 134 weeks. Baseline prescribing error data were collected on weekdays for all patients for a period of 32 weeks, following which the ZTP policy was introduced. Daily error feedback was introduced after a further 12 months. Errors were sub-classified as 'clinical', 'non-clinical' and 'infusion prescription' errors and the effects of interventions considered separately.
resultsThe baseline combined prescribing error rate was 892 (95 % confidence interval (CI) 765-1,019) errors per 1,000 PICU occupied bed days (OBDs), comprising 25.6 % clinical, 44 % non-clinical and 30.4 % infusion prescription errors. The combined interventions of ZTP plus daily error feedback were associated with a reduction in the combined prescribing error rate to 447 (95 % CI 389-504) errors per 1,000 OBDs (p < 0.0001), an absolute risk reduction of 44.5 % (95 % CI 40.8-48.0 %). Introduction of the ZTP policy was associated with a significant decrease in clinical and infusion prescription errors, while the introduction of daily error feedback was associated with a significant reduction in non-clinical prescribing errors.
conclusionThe combined interventions of ZTP and daily error feedback were associated with a significant reduction in prescribing errors in the PICU, in line with Department of Health requirements of a 40 % reduction within 5 years.
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Identifiers
22885650What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.