ArticlePrimary care respiratory journal : journal of the General Practice Airways Group2012
Patient-centred assessment of COPD in primary care: experience from a cross-sectional study of health-related quality of life in Europe.
Article in Primary care respiratory journal : journal of the General Practice Airways Group, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 43 citations in OpenAlex.
- The Effect of Aclidinium on Symptoms Including Cough in Chronic Obstructive Pulmonary Disease: A Phase 4, Double-Blind, Placebo-controlled, Parallel-Group Study.American journal of respiratory and critical care medicine · 2019Trial
- Management of Cough in Patients with Chronic Obstructive Pulmonary Disease: Results of the Multicenter Randomized Placebo-Controlled Clinical Trial.International journal of chronic obstructive pulmonary diseaseTrial
- Validity of the Chronic Airways Assessment Test (CAAT) in asthma, asthma+COPD and COPD in NOVELTY.ERJ open research · 2025Article
- [Use of long-acting triple therapy for chronic obstructive pulmonary disease (COPD) in practice: The ELETHON physicians' survey].Pneumologie (Stuttgart, Germany) · 2025Article
- Empowering the Patient With Chronic Obstructive Pulmonary Disease: Optimizing Inhalation Technique.Cureus · 2025Article
- Chronic Cough Patient Perspective: questionnaire validation and symptom impact.ERJ open research · 2025Article
- Cough in chronic lung disease: a state of the art review.Journal of thoracic disease · 2023Review
- Development of the Diaphragmatic Paralysis Questionnaire: a simple tool for patient relevant outcome.Interactive cardiovascular and thoracic surgery · 2021Article
- Correlation between disease severity factors and EQ-5D utilities in chronic obstructive pulmonary disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Minimal Clinically Important Differences for Patient-Reported Outcome Measures of Cough and Sputum in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2020Observational
- Inaccurate diagnosis of COPD: the Welsh National COPD Audit.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- New developments in optimizing bronchodilator treatment of COPD: a focus on glycopyrrolate/formoterol combination formulated by co-suspension delivery technology.International journal of chronic obstructive pulmonary disease · 2018Review
- Evaluation of the psychometric properties of the Early Morning Symptoms of COPD Instrument (EMSCI).International journal of chronic obstructive pulmonary disease · 2018Article
- Understanding the impact of symptoms on the burden of COPD.Respiratory research · 2017Review
- Drugs for chronic obstructive pulmonary disease.Australian prescriber · 2017Review
- POPE study: rationale and methodology of a study to phenotype patients with COPD in Central and Eastern Europe.International journal of chronic obstructive pulmonary disease · 2016Observational
- For better or for worse: a longitudinal study on dyadic coping and quality of life among couples with a partner suffering from COPD.Journal of behavioral medicine · 2015Article
- Identification of Anxiety Symptom Clusters in Patients with COPD: Implications for Assessment and Treatment.International journal of behavioral medicine · 2015Article
- Article
- Comorbidity and health-related quality of life in patients with severe chronic obstructive pulmonary disease attending Swedish secondary care units.International journal of chronic obstructive pulmonary disease · 2015Article
Corrections and comments
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Authors and funding
11 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost patients with chronic obstructive pulmonary disease (COPD) in Europe are treated in primary care, but perceptions on what guides primary care physicians (PCPs) in managing patients are lacking.
aimsTo describe factors associated with the assessment by PCPs of COPD severity and those associated with impaired health status, as assessed by patient-reported outcomes.
methodsThis cross-sectional study evaluated health-related quality of life (HRQL) in 2,294 COPD patients from five European countries. The severity of COPD was clinically judged by the PCPs and GOLD stage severity was calculated using spirometry data.
resultsPCPs' categories of severity reflected a wider range of HRQL scores (St George's Respiratory Questionnaire (SGRQ) total score: mild 30.3; moderate 41.7; severe 55.0; very severe 66.1) than GOLD severity grading (Stage I 38.2; Stage II 41.1; Stage III 49.9; Stage IV 58.5). Multiple ordinal logistic regression models showed that factors most closely related to PCP-rated COPD severity were Medical Research Council (MRC) dyspnoea grade, forced expiratory volume in 1 second (FEV₁) percent predicted, HRQL score (either SGRQ or COPD Assessment Test (CAT)), and previous hospitalisations (model generalised R²=0.45 or 0.44 (SQRQ or CAT in model, respectively); all factors p<0.0001). Factors with the highest association with HRQL scores (SGRQ or CAT) were MRC dyspnoea grade, COPD severity (PCP-rated), sputum production, and number of co-morbidities (model R²=0.46 or 0.37 (SQRQ or CAT in multiple linear regression model, respectively); all factors p<0.0001).
conclusionsPCPs successfully graded COPD severity clinically and appeared to have greater discriminative power for assessing severity in COPD than FEV₁-based staging. Their more holistic approach appeared to reflect the patients' HRQL rating and was consistent across five European countries.
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