ArticleJournal of biomechanics2012
Shear strength behavior of human trabecular bone.
Article in Journal of biomechanics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of Finite Element Analysis in Running Footwear Biomechanics: Insights for Running-Related Musculoskeletal Injuries.Journal of sports science & medicine · 2025Pooled it
- Occlusion-activated autonomous piezoelectric implants for adaptive prevention of peri-implantitis.Nature communications · 2026Article
- Evaluation of finite element modeling methods for predicting compression screw failure in a custom pelvic implant.Frontiers in bioengineering and biotechnology · 2024Article
- 3D-Printed PEEK/Silicon Nitride Scaffolds with a Triply Periodic Minimal Surface Structure for Spinal Fusion Implants.ACS applied bio materials · 2023Article
- Prospect of Metal Ceramic (Titanium-Wollastonite) Composite as Permanent Bone Implants: A Narrative Review.Materials (Basel, Switzerland) · 2021Review
- Efficient materially nonlinearBiomechanics and modeling in mechanobiology · 2020Article
- Complex biomechanical properties of non-augmented and augmented pedicle screws in human vertebrae with reduced bone density.BMC musculoskeletal disorders · 2020Article
- Using Non-linear Homogenization to Improve the Performance of Macroscopic Damage Models of Trabecular Bone.Frontiers in physiology · 2018Article
- Effect of including damage at the tissue level in the nonlinear homogenisation of trabecular bone.Biomechanics and modeling in mechanobiology · 2017Article
- Evaluation of Singh Index and Osteoporosis Self-Assessment Tool for Asians as risk assessment tools of hip fracture in patients with type 2 diabetes mellitus.Journal of orthopaedic surgery and research · 2017Article
- Effect of screw position on load transfer in lumbar pedicle screws: a non-idealized finite element analysis.Computer methods in biomechanics and biomedical engineering · 2017Article
- The roles of architecture and estrogen depletion in microdamage risk in trabecular bone.Journal of biomechanics · 2016Article
- Fixation of a split fracture of the lateral tibial plateau with a locking screw plate instead of cannulated screws would allow early weight bearing: a computational exploration.International orthopaedics · 2016Article
- The sensitivity of nonlinear computational models of trabecular bone to tissue level constitutive model.Computer methods in biomechanics and biomedical engineering · 2016Article
- Finite Element Analysis of Foot and Ankle Impact Injury: Risk Evaluation of Calcaneus and Talus Fracture.PloS one · 2016Article
- Glucagon-like peptide-1(GLP-1) receptor agonists: potential to reduce fracture risk in diabetic patients?British journal of clinical pharmacology · 2016Review
- Biomechanics and mechanobiology of trabecular bone: a review.Journal of biomechanical engineering · 2015Review
- The quartic piecewise-linear criterion for the multiaxial yield behavior of human trabecular bone.Journal of biomechanical engineering · 2015Article
- The effects of tensile-compressive loading mode and microarchitecture on microdamage in human vertebral cancellous bone.Journal of biomechanics · 2014Article
- Osteoporosis, fractures, and diabetes.International journal of endocrinology · 2014Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The shear strength of human trabecular bone may influence overall bone strength under fall loading conditions and failure at bone-implant interfaces. Here, we sought to compare shear and compressive yield strengths of human trabecular bone and elucidate the underlying failure mechanisms. We analyzed 54 specimens (5-mm cubes), all aligned with the main trabecular orientation and spanning four anatomic sites, 44 different cadavers, and a wide range of bone volume fraction (0.06-0.38). Micro-CT-based non-linear finite element analysis was used to assess the compressive and shear strengths and the spatial distribution of yielded tissue; the tissue-level constitutive model allowed for kinematic non-linearity and yielding with strength asymmetry. We found that the computed values of both the shear and compressive strengths depended on bone volume fraction via power law relations having an exponent of 1.7 (R(2)=0.95 shear; R(2)=0.97 compression). The ratio of shear to compressive strengths (mean±SD, 0.44±0.16) did not depend on bone volume fraction (p=0.24) but did depend on microarchitecture, most notably the intra-trabecular standard deviation in trabecular spacing (R(2)=0.23, p<0.005). For shear, the main tissue-level failure mode was tensile yield of the obliquely oriented trabeculae. By contrast, for compression, specimens having low bone volume fraction failed primarily by large-deformation-related tensile yield of horizontal trabeculae and those having high bone volume failed primarily by compressive yield of vertical trabeculae. We conclude that human trabecular bone is generally much weaker in shear than compression at the apparent level, reflecting different failure mechanisms at the tissue level.
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